Results 131 to 140 of about 2,712,257 (268)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Kommerzielle Open Access Publishing-Geschäftsmodelle auf dem Prüfstand: ökonomische Zwischenbilanz der

open access: yesGMS Medizin – Bibliothek – Information, 2006
Librarians amongst many others point towards Open Access Publishing as being the loophole in the current library and journal crisis. However, Open Access Publishing could entail higher costs for the university as a whole even though spendings for ...
Bauer, Bruno
doaj  

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Principles of Best Practice and Transparency in Scholarly Publishing ver. 4: a Korean translation [PDF]

open access: yesThe Ewha Medical Journal
The Committee on Publication Ethics, DOAJ, the Open Access Scholarly Publishing Association, the World Association of Medical Editors
doaj   +1 more source

What should urologists know about Pseudojournals and open access publishing? A narrative review of the literature. [PDF]

open access: yesIndian J Urol, 2022
Jena R   +5 more
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Learned society attitudes towards open access [PDF]

open access: yes
Learned societies are “a critical part of the research environment ”, and many rely largely on subscription income from their journals publishing programme to support the other services they offer to their members in the promotion of their academic dis c

core  

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