Results 331 to 340 of about 2,750,739 (393)
CINs of the cytoplasm: dissecting dsRNA signaling in chromosomal instability
Molecular Oncology, EarlyView.Micronuclei, formed during cell division in chromosomal instability settings, rupture and lead to the accumulation of immunogenic double‐stranded RNA in the cytoplasm, activating MAVS‐dependent interferon signaling and innate antitumor immunity.
Aglaia Skolariki +2 more
wiley +1 more source
FEBS Open Bio, Volume 15, Issue 4, Page 580-586, April 2025.Activation of amino acids by aminoacyl‐tRNA synthetases can be followed by a modified ATP/PPi exchange assay using radiolabelled γ‐[32P]ATP. The reaction is quenched at certain time points, followed by separation of the product ([32P]PPi) from the substrate (γ‐[32P]ATP) by thin‐layer chromatography (TLC).
Igor Živković +4 more
wiley +1 more source
eGEMs' Early Adventures in Open Access Publishing. [PDF]
EGEMS (Wash DC), 2014 Holve E.
europepmc +1 more source
Understanding and measuring mechanical signals in the tumor stroma
FEBS Open Bio, EarlyView.This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz +3 more
wiley +1 more source
Development of a publishing framework for living open access textbooks1
, 2012 Anita Eppelin, Richarda Böttcher
openalex +2 more sources
FEBS Open Bio, Volume 15, Issue 4, Page 661-673, April 2025.Compared to normal tissues, NPC1 expression is significantly elevated in hepatocellular carcinoma tissues. Our findings indicate that NPC1 plays a key role in regulating neutrophil recruitment within the tumor, which is a critical factor in the progression of hepatocellular carcinoma and is closely linked to poor patient outcomes.
Songhai Yang +3 more
wiley +1 more source
FEBS Open Bio, Volume 15, Issue 4, Page 599-607, April 2025.Method for Frailty Score (FS) calculation: (1) Combine all animals that will be compared in one group; (2) Calculate 20% cutoff; (3) Determine the number of animals that ‘failed’ or ‘passed’; (4) Calculate ‘percentage of success’ for graphical representation of parameters; (5) Repeat for all parameters; (6) Calculate FS and use percentages for ...
Aleksandra Mladenovic, Smilja Pracer
wiley +1 more source
Real‐world genomic landscape of colon and rectal cancer
FEBS Open Bio, Volume 15, Issue 4, Page 674-685, April 2025.We confirmed enrichment of RTK alterations in patients with RAS/BRAF‐wt tumors and of PI3K pathway alterations in RAS/BRAF‐altered tumors with 51 982 real‐world tissue comprehensive genomic profiling (CGP) samples in CRC. In a subset of 140 patients with both tissue and liquid results, the sensitivity of liquid for results found by tissue was 100% when
Markus Schulze +7 more
wiley +1 more source
FEBS Open Bio, Volume 15, Issue 4, Page 587-598, April 2025.Mitophagy, the selective degradation of damaged mitochondria, is crucial for cellular health and function. This study introduces a rapid and efficient flow cytometry method using GFP‐BNIP3L/NIX to accurately quantify mitophagy. Our approach can be adapted to use any fluorescent‐tagged selective autophagy receptor, enabling direct and rapid analysis of ...
Mija Marinković +3 more
wiley +1 more source