Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Cultivated Vegetation Shapes Diversity and Stability of Spontaneous Herbaceous Communities in Residential Green Spaces. [PDF]
Peng J, Liu J, Huang Z.
europepmc +1 more source
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
Intelligent Tutoring Systems for Adult Learning in STEM Disciplines
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley +1 more source
Radical Spaces. Value, identity and perception of open green spaces in the Randstad
In light of extreme urbanization trends, this paper summarizes the conclusions of a three-month research collaboration facilitated by the Creative Industries Fund NL under the Building Talent program and addresses the big challenge of preserving contested undefined open green space.
Isabel Recubenis Sanchis +2 more
openaire +1 more source
Assessing human-scale green equity in the 15-minute city using street-view-based visual landscape indicators and explainable machine learning: a case study of Chengdu, China. [PDF]
Yan S, Ma Y, Wang X.
europepmc +1 more source
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Exploring the relationship between mental health and urban green space soundscapes: A scoping review. [PDF]
Ahmadi E +8 more
europepmc +1 more source
Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati +10 more
wiley +1 more source
Spatiotemporal modeling of urban green space connectivity and landscape structure for climate adaptation in Tehran, Iran. [PDF]
Omidighalehmohammadi Z +3 more
europepmc +1 more source

