Results 141 to 150 of about 101,208 (262)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Disaster-resilient cities and open green spaces

open access: yes
The rapid and unplanned urbanization processes worldwide intensify the adverse impacts of physical, social, and environmental factors, rendering cities more vulnerable. Balancing the numerous economic, environmental, administrative, and social elements within cities and reducing their vulnerability to become resilient against stress and shocks have ...
Demiroğlu, Demet   +3 more
openaire   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Analysis of The Availability of Urban Green Open Space

open access: yesProceedings of the 3rd International Seminar on Tourism (ISOT 2018), 2019
Mamat Ruhimat, Riyan Zainudin
openaire   +1 more source

Migration- refugees and open-green spaces: Kilis case/Turkey

open access: yes, 2019
Today most important migration movement is taking place in Syria due to the civil war. Most of the Syrian asylum-seekers have sought refuge in Turkey. The migration has led to many problems in the areas such as physical, social, cultural and economical in the country. One of these areas is urban open and green spaces.
Demiroğlu, Demet   +3 more
openaire   +3 more sources

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

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