Results 81 to 90 of about 140,263 (244)

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Overlooked potentials of open spaces – new types and categories of urban landscapes [PDF]

open access: yesUrbani Izziv, 2001
Cities possess numerous overlooked and under-utilised potential spaces for organising green surfaces and open urban spaces. They are defined by their position in the city, adequate contents nearby that could attract visitors and actual availability of ...
Ina Šuklje Erjavec
doaj  

Role Of Green Open Space In Performance Improvement Of Malang City Center

open access: yesJournal of Innovation and Applied Technology, 2018
This study is a continuation of previous research [5],[6],[7], on the hierarchy of the Green Open Space’s role of the city based on its 9 classifications (Green Line, City Park, Urban forest, Garden Tomb, Sports Park, Rotonde, Monument Park, Playground ...
subhan ramdlani, Lisa Dwi Wulandari
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

The environmental benefits of urban open green spaces [PDF]

open access: yes, 2017
Most of the scientific papers on urban planning and sustainable development begin by emphasizing the multiple benefits of urban open green space. When it comes to the benefits of urban green and open space, one should concern on the facilities provided ...
Husna Zayadi
core   +3 more sources

Urban Green Spaces. Facilities or infrastructure?

open access: yes, 2012
The establishment of urban green spaces in Spanish planning EMERGES as AN OBLIGATION FOR urban PLANNERS and are considered as "endowments". The LAND ACT 1956 conceived the open spaces system as a "green area" and a minimum reservation module of 10% of ...
Fariña Tojo, José
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Urban Greening Through Participatory Governance: Managing Green Open Spaces in Bekasi, Indonesia [PDF]

open access: yesE3S Web of Conferences
Rapid urbanisation poses a major challenge for cities in Indonesia in maintaining green open spaces as part of sustainable urban planning. The city of Bekasi is a case in point, where despite an increase of green open spaces, this achievement has not yet
Safitri Nur Dewi, Kholid Anwar
doaj   +1 more source

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