Results 111 to 120 of about 126,493 (296)

Value of urban green spaces in promoting healthy living and wellbeing: prospects for planning

, 2015
Andrew Chee Keng Lee,1 Hannah C Jordan,1 Jason Horsley2 1Section of Public Health, School of Health and Related Research, University of Sheffield, 2Sheffield City Council, Sheffield, UK Abstract: There has been considerable work done in recent years ...
Lee ACK, Horsley J, Jordan HC
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Urban Greening Through Participatory Governance: Managing Green Open Spaces in Bekasi, Indonesia [PDF]

E3S Web of Conferences
Rapid urbanisation poses a major challenge for cities in Indonesia in maintaining green open spaces as part of sustainable urban planning. The city of Bekasi is a case in point, where despite an increase of green open spaces, this achievement has not yet
Safitri Nur Dewi, Kholid Anwar
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Spatial Distribution and Quality Status of Open Green Spaces and Parks in Calabar Metropolitan Area, Cross River State, Nigeria

Studia Ecologiae et Bioethicae
Urban green areas are often seen in highly developed countries as urban green lungs because of their ability to mediate between man and nature. However, it is not the case in developing countries, where the means of subsistence are considered pivotal ...
Josiah Nwabueze Obiefuna, Ebin Okah Inah, Maurice Paul Nkong, Ame Edet Ekong   +3 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

How blue-green coastal landscapes shape runners' perceptions: A deep-learning street-view study of Qingdao's coastal greenway

Journal of Urban Management
With rapid urbanization, understanding how coastal blue-green landscapes support health-oriented physical activity has become increasingly important. Using the 21.25 km coastal greenway in Qingdao as a case study, this research examines how the visual ...
Xi Peng, Xin Chen, Sha Li
doaj   +1 more source

Use pattern analysis in green open spaces of Malaysia [PDF]

, 2013
Housing development in Malaysia is bounded to obey several acts and legislation which among them is the Planning Guidelines and Standards set out by the Town and Country Planning Department of Malaysia. This guideline serves as a written statement that
Abdul Malek, Nurhayati
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Post-Earthquake Urban Planning in Türkiye: Evaluating Disaster Refuge Systems in Hatay and Istanbul

Journal of Architectural Sciences and Applications
Countries prone to significant earthquakes often develop disaster refuge and relief urban park systems to enhance urban open green spaces, which serve as temporary shelters for evacuation after seismic events.
Büşra Nur Gök, Gizem Dinç
doaj   +1 more source