Results 91 to 100 of about 136,516 (290)
Using Green Open Spaces to Support Campus Academic Activities
Green open space has many advantages, including acting as an effective air filter, maintaining groundwater availability, and preserving flora and fauna.
Dayanti, N. (Neni) +7 more
core
Urban streams as focal points of urban regeneration: The area of Konstantinidis stream in Toumba, Thessaloniki [PDF]
Nowadays, the concept of Green Infrastructure (GI) is having a big impact when it comes to planning cities and to policymaking, due to the need for substantial rethinking of urban development and for a contemporary way to respond to the current ...
Kastanidou Symela +1 more
doaj +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Landscape Fragmentation and Accessibility of Green Spaces [PDF]
To improve the positive effects provided by green spaces on human well-being in dispersed urban areas is a key challenge for sustainable spatial development in Europe. This article presents a methodology that allows for the comparison of the potential of
Wandl, Alexander
core +1 more source
Overlooked potentials of open spaces – new types and categories of urban landscapes [PDF]
Cities possess numerous overlooked and under-utilised potential spaces for organising green surfaces and open urban spaces. They are defined by their position in the city, adequate contents nearby that could attract visitors and actual availability of ...
Ina Šuklje Erjavec
doaj
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source

