How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Green open space planning based on spatial justice in Jakarta: Study of child friendly integrated public spaces/RPTRA and general green open space [PDF]
Background: Urbanization has significantly reduced green open spaces in Jakarta, impacting ecological balance and quality of life. While the importance of green open spaces for urban quality of life is well understood, comprehensive studies on spatial ...
Saputra, Erlangga +1 more
core +3 more sources
Urban streams as focal points of urban regeneration: The area of Konstantinidis stream in Toumba, Thessaloniki [PDF]
Nowadays, the concept of Green Infrastructure (GI) is having a big impact when it comes to planning cities and to policymaking, due to the need for substantial rethinking of urban development and for a contemporary way to respond to the current ...
Kastanidou Symela +1 more
doaj +1 more source
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Using Green Open Spaces to Support Campus Academic Activities
Green open space has many advantages, including acting as an effective air filter, maintaining groundwater availability, and preserving flora and fauna.
Dayanti, N. (Neni) +7 more
core
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Ecological Resilience Through Green Infrastructure: Analyzing the Role of Private Green Open Spaces in Tropical Megacities [PDF]
Green open space is decreasing along with urban development. Development in urban areas has an impact on reducing green land which is important for urban resilience.
Inavonna, Inavonna +7 more
core +1 more source

