Results 41 to 50 of about 16,435,465 (197)

Biomarkers of primary open-angle glaucoma [PDF]

Expert Review of Ophthalmology, 2010
Primary open-angle glaucoma (POAG) is a primary neuronal disease of the optic nerve without a definable cause, and is often associated with increased intraocular pressure. Worldwide, POAG is the second leading cause of blindness; there are 45 million people today with POAG and bilateral blindness is present in 4.5 million of these.
Paul A, Knepper, John R, Samples, Beatrice Yjt, Yue   +2 more
openaire   +2 more sources

Systemic medications and other risk factors of open-angle glaucoma [PDF]

, 2012
Het onderzoek in dit proefschrift is ontworpen om de werking van sommige systemische geneesmiddelen te ontcijferen en een aantal andere risicofactoren van open-kamerhoek glaucoom (OKG) te onderzoeken.
Marcus, Michael Williams, Marcus, Michael Williams,   +1 more
core   +1 more source

Artificial Intelligence in Ophthalmology: From Methodological Advances to Clinical Translation and Future Directions

Eye &ENT Research, EarlyView.
ABSTRACT Artificial intelligence (AI) is reshaping ophthalmology from task‐specific image analysis toward multimodal, longitudinal, and clinically integrated decision support. This narrative review summarizes the methodological evolution of ophthalmic AI, including traditional machine learning, task‐specific deep learning, self‐supervised learning ...
Yuxin Liu, Hanruo Liu
wiley   +1 more source

Artificial Intelligence in Optical Coherence Tomography‐Based Ophthalmic Imaging: From Automated Diagnosis to Personalized Disease Monitoring

Eye &ENT Research, EarlyView.
ABSTRACT Artificial intelligence (AI) is increasingly applied to optical coherence tomography (OCT) in ophthalmology, but evidence for automated diagnosis is stronger than evidence for longitudinal monitoring. This narrative review evaluates OCT‐based AI with emphasis on disease monitoring and progression, particularly in retinal disease and glaucoma ...
Stjepan Škudar
wiley   +1 more source

Developing the clinical components of a complex intervention for a glaucoma screening trial : a mixed methods study [PDF]

, 2011
Peer ...
Vale, Luke D, Burr, JM, Campbell, MK, Francis, JJ, McCann, Sharon K., Azuara-Blanco, Augusto; id_orcid, Campbell, S. E., Hopkins, D, Greene, A, Hernández, Rodolfo, McCann, SK, Francis, Jillian J., Glaucoma Screening Platform Study, Hopkins, Debra, Campbell, SE, Campbell, Marion K, Francis, Jillian J, Vale, LD, Campbell, Marion K., McCann, Sharon K, Hernández, R, Francis, J., McCann, S. K., Glaucoma screening Platform Study group, Hernandez, R. A., Vale, Luke D., Burr, J. M., Hopkins, D., Campbell, Susan E, Campbell, M. K., Burr, Jennifer M., null null, Greene, Alexandra, Burr, Jennifer M, Campbell, Susan E., Greene, A., Vale, L. D.   +36 more
core   +2 more sources

Artificial Intelligence for Distinguishing Glaucoma From Its Mimickers: A Narrative Review of Diagnostic Pitfalls, Validation Gaps, and Clinical Translation

Eye &ENT Research, EarlyView.
ABSTRACT Artificial intelligence (AI) has advanced rapidly in glaucoma, but many models remain optimized for case‐control detection rather than the clinically harder task of distinguishing glaucoma from its mimickers. This narrative review primarily examined literature published from January 2018 to March 2026 on glaucoma AI, difficult comparator ...
Cansu Yüksel Elgin
wiley   +1 more source

Engineering mRNA‐LNP Medicines for the Ageing Brain: Opportunities and Challenges for Neurodegenerative Diseases

Exploration, EarlyView.
This review highlights recent advances in engineering messenger RNA (mRNA)‐lipid nanoparticles (LNPs) to cross the ageing blood–brain barrier and target neurodegenerative diseases. It outlines design principles, delivery routes, and translational challenges, charting a roadmap towards clinical application of mRNA‐LNP therapeutics for neurodegenerative ...
Abdel Ali Belaidi, Denzil L. Furtado, Francesca Alves, Rebecca M. Nisbet, Scott Ayton, Ashley I. Bush   +5 more
wiley   +1 more source

Peripapillary schisis in open-angle glaucoma [PDF]

Eye, 2016
PurposeTo report clinical features, topographic findings and outcome of 10 eyes with peripapillary schisis in open-angle glaucoma.Patients and methodsA retrospective review of patients with open-angle glaucoma who were noted to have peripapillary schisis on optical coherence tomography (OCT) were included.
N, Dhingra, R, Manoharan, S, Gill, M, Nagar   +3 more
openaire   +2 more sources

Pharmacogenetics of ophthalmic topical β-blockers [PDF]

, 2008
Glaucoma is the second leading cause of blindness worldwide. The primary glaucoma risk factor is elevated intraocular pressure. Topical β-blockers are affordable and widely used to lower intraocular pressure.
Smith, Edward M., Wilke, Russell A., Sidjanin, Duska J., McCarty, Catherine A., Patchett, Richard   +4 more
core   +1 more source

Optic Nerve Thickness Assessed by Ocular Ultrasonography in Obstructive Sleep Apnea

Journal of Ultrasound in Medicine, EarlyView.
Objectives Obstructive sleep apnea (OSA) has been associated with various ocular complications, yet ultrasonographic evaluation of optic nerve thickness and its relationship with nocturnal hypoxemia remains poorly understood. This study aimed to evaluate optic nerve thickness and globe dimensions using ocular ultrasonography in patients with different ...
Buğra Kerget, Eyüp Çetin, Alperen Aksakal, Sırma Merve Çetin, Mustafa Buğra Coşkuner   +4 more
wiley   +1 more source