Results 81 to 90 of about 16,435,465 (197)

Risk of open angle glaucoma due to tumor necrosis factor alpha gene polymorphisms

open access: yesElectronic Physician, 2016
Introduction: Axonal degeneration and retinal ganglion cell apoptosis in glaucoma is associated with tumor necrosis factor alpha (TNF-α), which is an important pro-inflammatory cytokine.
Mona Abdel Hamid   +4 more
doaj   +1 more source

Adult‐onset Coats disease: A systematic review and meta‐analysis of imaging biomarkers and targeted therapies

open access: yesActa Ophthalmologica, EarlyView.
Abstract Coats disease diagnosed in adulthood is a rare idiopathic retinal telangiectatic vasculopathy that may differ in phenotype from childhood‐diagnosed cases. This systematic review synthesizes current evidence to characterize its clinical spectrum, imaging features, treatment outcomes and underlying mechanisms, with a focus on immunovascular ...
Catarina Francisco   +2 more
wiley   +1 more source

Protein misfolding and mitochondrial dysfunction in glaucoma

open access: yesFrontiers in Cell and Developmental Biology
Glaucoma is a leading cause of irreversible blindness worldwide. Elevated intraocular pressure caused by restricted outflow of the aqueous humor leads to the degeneration of retinal ganglion cells (RGCs) and their axons.
Arunkumar Venkatesan   +2 more
doaj   +1 more source

When to operate on open angle glaucoma [PDF]

open access: yesEye, 1987
The aim of treatment in primary angle glaucoma should be to reduce the intraocular pressure throughout the 24 hours to a level where no damage is done to the optic nerve head, thus preventing any field defect. Open angle glaucoma as it is presently defined requires a significantly raised intraocular pressure to be associated with detectable changes in ...
openaire   +2 more sources

Endocrine Dysfunction in Open Angle Glaucoma

open access: yesKlinische Monatsblätter für Augenheilkunde, 2021
AbstractThe eye, like all organs, is exposed to the effects of the bodyʼs endocrine system. In addition, however, local branches of the endocrine system control important organ-specific functions, such as the production and drainage of aqueous humour.
openaire   +3 more sources

Real‐world insights on switching aflibercept dosage for enhanced outcomes in age‐related macular degeneration (RISE‐AMD): Safety data

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To evaluate real‐world safety experience with aflibercept 8 mg in a large case series of patients with neovascular age‐related macular degeneration (nAMD). Methods Due to a high proportion of patients on short treatment intervals, patients with nAMD at a Danish tertiary retina clinic were systematically switched to aflibercept 8 mg ...
Mary Graciya Karunainathan   +12 more
wiley   +1 more source

Epidemiological characterization of primary open-angle glaucoma

open access: yesMedisur, 2010
Background: The primary open-angle glaucoma is a problem for public health all over the world. It is a silent and slowly progressive disease leading to blindness.
Leonor Rosario Díaz Alfonso   +4 more
doaj   +2 more sources

The role of the local and general somatic factors for the open-angle glaucoma development in patients with eye manifestations of pseudoexfoliation syndrome

open access: yesОфтальмохирургия, 2013
Pseudoexfoliation syndrome (PEX) is one of the best known triggers of glaucoma. The development of the open-angle glaucoma only in some patients with the PEX with definite local and general risk factors requires a further research. Purpose.
V.V. Agafonova,   +4 more
doaj  

Risk Factors for Primary Open-Angle Glaucoma in Western Turkey [PDF]

open access: yes, 2013
Pur po se: To evaluate the prevalence of primary open-angle glaucoma (POAG) in subjects aged over 40 years in Western Turkey and to quantify its association with several systemic risk factors.
Tuncay Küsbeci   +13 more
core   +1 more source

Real‐world incidence and clinical characteristics of intraocular inflammation following intravitreal faricimab therapy: A safety study

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To estimate the real‐world incidence of intraocular inflammation (IOI) following intravitreal faricimab injections at a large, highly specialized tertiary centre. Methods Single‐centre, retrospective cohort study with chart review using an electronic injection database and electronic medical records from November 2023 to August 2024 ...
Miklos Schneider   +7 more
wiley   +1 more source

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