Results 61 to 70 of about 47,334 (242)

Effect of carbamazepine on the pharmacokinetics of vepdegestrant, a PROteolysis TArgeting Chimera estrogen receptor degrader, in healthy adults

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim To evaluate the effects of carbamazepine, a strong cytochrome P450 (CYP)3A4 inducer, on the pharmacokinetics and safety of vepdegestrant, a PROteolysis TArgeting Chimera estrogen receptor degrader. Methods This was a phase 1, open‐label, fixed‐sequence, two‐period study in healthy adult participants.
Hechuan Wang   +7 more
wiley   +1 more source

Ocrelizumab‐induced colitis: VigiBase disproportionality analysis, case reports and literature review

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Ocrelizumab is a humanized anti‐CD20 monoclonal antibody used in multiple sclerosis. Since its commercialization, several cases of ocrelizumab‐induced colitis have been reported in the scientific literature. Methods To explore the potential association of ocrelizumab with colitis as an adverse drug reaction (ADR), we conducted a descriptive and ...
Audrey Fresse   +3 more
wiley   +1 more source

Role of laparoscopic cholecystectomy in children

open access: yesJournal of Indian Association of Pediatric Surgeons, 2005
The present study is undertaken to establish the usefulness of laparoscopic cholecystectomy and to know its merits and demerits as compared to open cholecystectomy in children. In all, 28 patients who underwent cholecystectomy (8 open and 20 laparoscopic
Oak Sanjay   +4 more
doaj  

Primary hyperparathyroidism can generate recurrent pancreatitis and secondary diabetes mellitus – A case report [PDF]

open access: yes, 2019
Introduction. Acute or recurrent pancreatitis may be a complication of primary hyperparathyroidism and patients with previous episodes of pancreatitis may develop secondary diabetes mellitus. Case report.
Dănciulescu Miulescu, Rucsandra Elena   +4 more
core   +2 more sources

Study of early cholecystectomy for mild and moderate acute cholecystitis as per Tokyo Guideline

open access: yesAsian Journal of Medical Sciences, 2018
Background: According to Tokyo Guidelines, 2007 operative management of acute cholangitis and cholecystitis to be administered earlier with preference of laparoscopic cholecystectomy over conventional open cholecystectomy.
Mintu Mohan Nandi   +5 more
doaj   +1 more source

Limited post-operative narcotic use in elective laparoscopic cholecystectomy [PDF]

open access: yes, 2017
Purpose: To limit narcotics use Cochrane review: multiple studies have shown postoperative pain can be managed with non-narcotic meds with good outcome Less medication related side effects:N/V, constipation, disorientation Prevents substance addiction ...
Josloff, MD, Robert   +3 more
core   +1 more source

Clinical study of single-incision laparoscopic cholecystectomy [PDF]

open access: yes, 2013
We experienced 63 patients with non-inflammatory disease who underwent single-incision laparoscopic cholecystectomy (TANKO-LC). Herein we report the procedure of operation and the short-term results. We compared 63 cases of TANKO-LC with 109 cases of non-
Hamano, Ryousuke   +9 more
core   +1 more source

Evaluation of Ceftriaxone as a Monotherapy and Amoxicillin With Clavulanic Acid as Combination Therapy in Surgical Prophylaxis

open access: yesiNew Medicine, EarlyView.
ABSTRACT Surgical antibiotic prophylaxis (SAP) is crucial in preventing postoperative surgical site infections (SSIs), especially in clean and clean‐contaminated surgeries. It was a prospective comparative observational study that compared the effectiveness and safety of single‐dose ceftriaxone monotherapy with amoxicillin–clavulanic acid as a ...
Anayat Ullah   +5 more
wiley   +1 more source

FACTORS LEADING TO CONVERSION OF LAPAROSCOPIC CHOLECYSTECTOMY TO OPEN CHOLECYSTECTOMY

open access: yesPakistan Armed Forces Medical Journal, 2021
Objective: To evaluate the various factors leading to conversion of laparoscopic cholecystectomy to open cholecystectomy. Study Design: Comparative cross-sectional study.
Muhammad Zubair   +5 more
doaj  

Experience of Laparoscopic Cholecystectomies in a Tertiary Care Hospital: a Retrospective Study

open access: yesGalician Medical Journal, 2020
Introduction: Laparoscopic cholecystectomy is the most commonly performed surgical procedure of digestive tract. It has replaced open cholecystectomy as gold standard treatment for cholelithiasis and inflammation of gallbladder.
Aamir Hussain Hela   +3 more
doaj   +1 more source

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