Results 101 to 110 of about 443,609 (315)
Molecular Oncology, EarlyView.Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma +9 more
wiley +1 more source
Open Cluster Dynamics under the Influence of Outflow–Ambient Interactions
The Astrophysical JournalStars with outflows impinging on ambient gas experience accelerations due to the gravitational feedback from the interaction morphology between the outflow and the ambient gas.
Muxin Liu +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Extra-Tidal Members and Dynamics of the Open Cluster NGC 6705
Applied SciencesIn this study, we utilized Gaia-DR3 astrometric data combined with the density-based spatial clustering of applications with noise (DBSCAN) algorithm to thoroughly investigate the dynamics and extra-tidal members of the open cluster NGC 6705.
Chen Zhou, Xinhua Gao
doaj +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Robust Clustering of Open Access Journal Based on Scopus Journal Metrics Database
Lentera Pustaka: Jurnal Kajian Ilmu Perpustakaan, Informasi dan KearsipanBackground: Open-access is free online access to articles, journal, conferences proceedings, book series and trade journal which provides unrestricted and permit the users to read, download, print, copy and link to the articles.
Rizki Agung Wibowo +2 more
doaj +1 more source
Variability in the Massive Open Cluster NGC 1817 from K2: A Rich Population of Asteroseismic Red Clump, Eclipsing Binary, and Main-sequence Pulsating Stars. [PDF]
Astron J, 2020 Sandquist EL +15 more
europepmc +1 more source