Results 121 to 130 of about 458,301 (316)

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Robust Clustering of Open Access Journal Based on Scopus Journal Metrics Database

open access: yesLentera Pustaka: Jurnal Kajian Ilmu Perpustakaan, Informasi dan Kearsipan
Background: Open-access is free online access to articles, journal, conferences proceedings, book series and trade journal which provides unrestricted and permit the users to read, download, print, copy and link to the articles.
Rizki Agung Wibowo   +2 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Ultraviolet Variability in Solar-type Members of the M67 Open Cluster

open access: yesThe Astrophysical Journal
Solar-type members of the rich, nearly solar-age and solar-metallicity M67 open cluster are systematically investigated for ultraviolet variability. We utilize archival Galaxy Evolution Explorer (GALEX) data, which feature several imaging observation ...
Carl Melis, Ekamjot Kaire
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

FCIQMC-Tailored Distinguishable Cluster Approach: Open-Shell Systems

open access: hybrid, 2022
Eugenio Vitale   +3 more
openalex   +1 more source

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