Results 121 to 130 of about 443,609 (315)

The shape of nearby Open Clusters

open access: yes, 2019
We use new memberships from Gaia DR2 to investigate the shape of the nearest open clusters. We investigate their 2D distribution projected on the sky and fit two gaussians components on the central part and external envelope. For open clusters closer than 200 pc from the Sun, we fit 3D ellipsoids on the spatial distribution of the members.
Tarricq, Y.   +2 more
openaire   +3 more sources

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

The open cluster Tr 14

open access: yesAstrophysics and Space Science, 1983
New photoelectric UBVRI data for stars in the young open cluster Tr 14 in the Great Carina Nebula (NGC 3372) are presented. The two-color diagram separates clearly the member from the nonmember stars. Thus, the membership of about 39 stars is suggested.
openaire   +3 more sources

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

open access: yesMolecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez   +5 more
wiley   +1 more source

Searching for Radio Pulsars in Old Open Clusters from the Parkes Archive

open access: yesThe Astrophysical Journal
Motivated by the discovery of a pulsar in the direction of the old open cluster NGC 6791, we conducted a search for radio pulsars in archival Parkes observations targeting similar old open clusters. We reprocessed 224 observations totalling 75.02 hr from
S. B. Zhang   +9 more
doaj   +1 more source

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee   +9 more
wiley   +1 more source

Clustering Batik SMEs: Open Innovation for Environmental Sustainability

open access: yesEngineering Proceedings
Environmental sustainability is challenging for SMEs, mainly due to SMEs’ limited resources. To achieve environmental sustainability, SMEs must innovate their production process and waste management.
Amelia Kurniawati   +4 more
doaj   +1 more source

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