Results 121 to 130 of about 5,726,855 (364)

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Wide Field Multicolor CCD Photometry of the Open Cluster NGC752

Open Astronomy, 2010
The results of CCD photometry in the seven-color Vilnius system of 3058 stars down to V ~ 18.0 mag in a 1.5 square degree field around the cluster NGC 752 are presented.
Zdanavičius J., Bartašiutė S., Zdanavičius K.   +2 more
doaj   +1 more source

Open clusters in AurOB2

, 2016
We study the area around the HII region Sh 2-234, including the young open cluster Stock 8, to investigate the extent and definition of the association Aur OB2 and the possible role of triggering in massive cluster formation. We obtained Str mgren and J,H,Ks photometry for Stock 8 and Str mgren photometry for two other cluster candidates in the area,
Marco, A., Negueruela, I.
openaire   +2 more sources

Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284

FEBS Letters, EarlyView.
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli, Alex Fissore, Edoardo Salladini, Eleonora Raccuia, Simonetta Oliaro‐Bosso, Alessia Ruggiero, Rita Berisio, Milagros Medina, Adrian Velazquez‐Campoy, Salvatore Adinolfi, Mauro Marengo   +10 more
wiley   +1 more source

Basic Kinematics of the Galactic Disk from Open Cluster Data

Open Astronomy, 2016
The kinematic parameters of the Galactic disk are redetermined based on open-cluster data. It is shown that the Bottlinger-Oort model of pure circular rotation can be confidently used to describe the observed motions of disk objects at least out to ...
Loktin A. V., Popova M. E.
doaj   +1 more source

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

FEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen, Zenon Toprakcioglu, Michele Vendruscolo   +2 more
wiley   +1 more source

Stellar Variability toward the Galactic Open Cluster NGC 7209

The Astrophysical Journal
We present the analysis of stellar variability in an open cluster NGC 7209 using optical V -band CCD photometric observations. Out of 4499 stars in our study, we detected 284 candidate variables, including one identified previously.
Dorothy M. Mwanzia, Sneh Lata, W. P. Chen, Soumen Mondal, Geoffrey Okeng’o, John Buers, Samrat Ghosh, Athul Dileep, Arjav Jain, Alisher S. Hojaev, Santosh Joshi   +10 more
doaj   +1 more source

The orbit of the old, metal-rich, open cluster NGC 6791

EPJ Web of Conferences, 2012
We present a study of the Galactic orbit of the old, metal-rich open cluster NGC 6791. To recover its recent kinematical history we integrate the cluster’s orbit backward in a Milky Way (MW) model including bar and spiral structure.
Minchev I., Jílková L., Carraro G., Jungwiert B.   +3 more
doaj   +1 more source

β,β-Isomer of Open-Wells–Dawson Polyoxometalate Containing a Tetra-Iron(III) Hydroxide Cluster: [{Fe4(H2O)(OH)5}(β,β-Si2W18O66)]9−

Inorganics, 2016
The β,β-isomer of open-Wells–Dawson polyoxometalate (POM) containing a tetra-iron(III) cluster, K9[{Fe4(H2O)(OH)5}(β,β-Si2W18O66)]·17H2O (potassium salt of β,β-Fe4-open), was synthesized by reacting Na9H[A-β-SiW9O34]·23H2O with FeCl3·6H2O at pH 3, and ...
Satoshi Matsunaga, Eriko Miyamae, Yusuke Inoue, Kenji Nomiya   +3 more
doaj   +1 more source

Archaeal protein containing domain of unknown function 2193 undergoes oligomeric reconfiguration upon iron–sulfur cluster binding

FEBS Letters, EarlyView.
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter, James Larson, Monika Tokmina‐Lukaszewska, Jin Xiong, Jared Green, Yisong Guo, William E. Broderick, Brian Bothner, Joan B. Broderick   +8 more
wiley   +1 more source