Cerebras-GPT: Open Compute-Optimal Language Models Trained on the Cerebras Wafer-Scale Cluster [PDF]
, 2023 Nolan Dey +8 more
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Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
CCD Asteroseismology of Open Clusters [PDF]
, 1993 I. Vidal, Juan Antonio Belmonte
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Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Searching for Radio Pulsars in Old Open Clusters from the Parkes Archive
The Astrophysical JournalMotivated by the discovery of a pulsar in the direction of the old open cluster NGC 6791, we conducted a search for radio pulsars in archival Parkes observations targeting similar old open clusters. We reprocessed 224 observations totalling 75.02 hr from
S. B. Zhang +9 more
doaj +1 more source
Effectiveness of educational outreach visits compared with usual guideline dissemination to improve family physician prescribing-an 18-month open cluster-randomized trial. [PDF]
Implement Sci, 2018 Pinto D +5 more
europepmc +1 more source
WIYN Open Cluster Study. XCVII. An Extended Radial-Velocity Survey and Spectroscopic Binary Orbits in the Open Cluster NGC 188 [PDF]
Ramesh Narayan +3 more
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THE SPATIAL DISTRIBUTION OF STARS IN OPEN CLUSTERS [PDF]
, 2009 Néstor Sánchez +3 more
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