Results 141 to 150 of about 443,609 (315)
Collinder 121: a Young Southern Open Cluster Similar to H and χ Persei
A. Feinstein
openalex +1 more source
The open cluster NGC 4609 behind the Coalsack [PDF]
A. Feinstein, H. G. Marraco
openalex +1 more source
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi+12 more
wiley +1 more source
Radial Velocities and Spectral Types of Some Bright Blue Stars in the Old Open Cluster M67
Peter Pesch
openalex +1 more source
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh+5 more
wiley +1 more source
Photoelectric UVBY and Hα Photometry for the Praesepe Open Cluster
D. L. Crawford, Jason W. Barnes
openalex +1 more source
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha+10 more
wiley +1 more source
The Destiny of the Open Cluster NGC 6530: Past and Future
Studying the structures of open clusters is crucial for understanding stellar evolution and galactic dynamics. Based on Gaia DR3 data, we apply the hierarchical clustering algorithm to the young open cluster NGC 6530 and group its members into five ...
Delong Jia, Heng Yu, Zhengyi Shao, Lu Li
doaj +1 more source
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou+5 more
wiley +1 more source