Results 161 to 170 of about 5,900,834 (385)

On‐treatment dynamics of circulating extracellular vesicles in the first‐line setting of patients with advanced non‐small cell lung cancer: the LEXOVE prospective study

open access: yesMolecular Oncology, EarlyView.
The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina   +17 more
wiley   +1 more source

A preliminary comparison of photometric (MWSC) and trigonometric (TGAS) distances of open cluster stars

open access: yesOpen Astronomy, 2017
The goal of this researchwas to compare the open cluster photometric distance scale of the global survey of star clusters in the MilkyWay (MWSC) with the distances derived fromtrigonometric parallaxes fromthe Gaia DR1/TGAS catalogue and to investigate ...
Kovaleva Dana   +3 more
doaj   +1 more source

Tidal tails of open clusters

open access: yesAstronomy & Astrophysics
Context. Open clusters that emerged from the star-forming regions as gravitationally bound structures are subjected to star evaporation, ejection, and tidal forces throughout the rest of their lives. Consequently, they form tidal tails that can stretch kiloparsecs along the cluster’s orbit. Aims.
openaire   +3 more sources

Be stars in open clusters

open access: yesThe Astrophysical Journal Supplement Series, 1985
Rotational velocities and spectral types have been determined for Be stars in 12 open clusters in both the northern and the southern sky, and color-magnitude or H-R diagrams constructed for each from available photometric data. The location of the Be stars in the color-magnitude diagrams shows again that Be stars may exist in various evolutionary ...
openaire   +2 more sources

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

open access: yesMolecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam   +2 more
wiley   +1 more source

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

open access: yesMolecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang   +8 more
wiley   +1 more source

PSR J1922+37: a 1.9 s Pulsar Discovered in the Direction of the Old Open Cluster NGC 6791

open access: yesThe Astrophysical Journal Letters
More than 300 pulsars have been discovered in Galactic globular clusters; however, none have been found in open clusters. Here we present results from a 20 hr survey of seven open clusters with the Five-hundred-meter Aperture Spherical radio Telescope ...
Xiao-Jin Liu   +10 more
doaj   +1 more source

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

open access: yesMolecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park   +6 more
wiley   +1 more source

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