Results 171 to 180 of about 5,726,855 (364)
Spectral morphology in the open cluster NGC 2287 [PDF]
, 1979 H. Levato, S. Malaroda
openalex +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Searching for Radio Pulsars in Old Open Clusters from the Parkes Archive
The Astrophysical JournalMotivated by the discovery of a pulsar in the direction of the old open cluster NGC 6791, we conducted a search for radio pulsars in archival Parkes observations targeting similar old open clusters. We reprocessed 224 observations totalling 75.02 hr from
S. B. Zhang +9 more
doaj +1 more source
Clustering Batik SMEs: Open Innovation for Environmental Sustainability
Engineering ProceedingsEnvironmental sustainability is challenging for SMEs, mainly due to SMEs’ limited resources. To achieve environmental sustainability, SMEs must innovate their production process and waste management.
Amelia Kurniawati +4 more
doaj +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
Symposium: Astrometry I: On proper motions of open clusters
, 1962 S. Vasilevskis
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Molecular Oncology, EarlyView.Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source