Results 191 to 200 of about 5,726,855 (364)
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
Molecular Oncology, EarlyView.DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
wiley +1 more source
The Destiny of the Open Cluster NGC 6530: Past and Future
The Astronomical JournalStudying the structures of open clusters is crucial for understanding stellar evolution and galactic dynamics. Based on Gaia DR3 data, we apply the hierarchical clustering algorithm to the young open cluster NGC 6530 and group its members into five ...
Delong Jia, Heng Yu, Zhengyi Shao, Lu Li
doaj +1 more source
Radial Velocities and Spectral Types of Some Bright Blue Stars in the Old Open Cluster M67
, 1967 Peter Pesch
openalex +1 more source
ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
Molecular Oncology, EarlyView.In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee +9 more
wiley +1 more source
The Open Innovation Journey in Emerging Economies: An Analysis of the Brazilian Aerospace Industry
Journal of Aerospace Technology and Management, 2014 Open innovation is the systematic integration of collaborative, sourcing and revealing practices into a firm’s business strategy, which is not implemented at once, but through a journey. This paper investigates this subject in an emergent economy context,
Fabiano Armellini +2 more
doaj
Photoelectric UVBY and Hα Photometry for the Praesepe Open Cluster
, 1966 D. L. Crawford, Jason W. Barnes
openalex +1 more source
Radial velocity for the open cluster NGC 2420 [PDF]
, 1987 Tianxing Liu, K. A. Janes
openalex +1 more source
Molecular Oncology, EarlyView.This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima +6 more
wiley +1 more source
An extremely red star in the region of the young open cluster NGC 6231
, 1969 W. Seggewiß
openalex +1 more source
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Molecular Oncology, EarlyView.Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides +13 more
wiley +1 more source