Spinal Cord Abnormalities in Early Pediatric Multiple Sclerosis
ABSTRACT Spinal cord lesions and atrophy in the cervical region are common in adult multiple sclerosis (MS) and correlate with disability. Whether similar abnormalities occur in pediatric MS patients is largely unknown. Clinical and MRI evaluations were performed in 38 pediatric MS patients and 13 healthy controls (HC).
Monica Margoni+7 more
wiley +1 more source
Coronavirus research topics, tracking twenty years of research. [PDF]
Aryani A+21 more
europepmc +1 more source
Map-based trigonometric parallaxes of open clusters: The Praesepe
G. Gatewood, Joost Kiewiet de Jonge
openalex +1 more source
Compound Heterozygous MRPS14 Variants Associated With Leigh Syndrome
ABSTRACT MRPS14 (uS14m) is a nuclear‐encoded ribosomal protein important for mitochondria‐specific translation. To date, only a single individual with a recessive MRPS14‐related disorder (also known as COXPD38) has been reported. We report an additional subject possessing novel compound heterozygous MRPS14 variants (p.Asp37Asn, p.Asn60Asp). The subject
Maria Gabriela Otero+15 more
wiley +1 more source
A toolbox for the identification of foot-floor contact sequences to analyze atypical gait cycles in a real-life scenario: application on patients after proximal femur fracture and healthy elderly. [PDF]
Ghislieri M+5 more
europepmc +1 more source
CCD photometry of Andromeda IV - Dwarf irregular galaxy or M31 open cluster?
Joseph H. Jones
openalex +1 more source
Coffee Consumption Is Associated With Later Age‐at‐Onset of Parkinson's Disease
ABSTRACT Observation studies suggest that coffee consumption may lower the risk and delay the age‐at‐onset (AAO) of Parkinson's disease (PD). The aim of this study was to explore the causal relationship and genetic association between coffee consumption and the AAO, risk, and progression of PD. Using Mendelian randomization, we identified a significant
Dariia Kuzovenkova+3 more
wiley +1 more source
Identification of novel compounds with prophylactic activity against hypnozoites using a <i>Plasmodium cynomolgi in vitro</i> model. [PDF]
Zeeman A-M+9 more
europepmc +1 more source
Actionable Wearables Data for the Neurology Clinic: A Proof‐of‐Concept Tool
ABSTRACT Objective Wearable devices can monitor key health and fitness domains. In multiple sclerosis (MS), monitoring step count and sleep is feasible, valid, and offers a holistic glimpse of patient functioning and worsening. However, data generated from wearables are typically unavailable at the point of care.
Nicolette Miller+12 more
wiley +1 more source
Medicines support and social prescribing to address patient priorities in multimorbidity (MIDAS): protocol for a definitive, multi-arm, cluster randomised, controlled trial in Irish general practice. [PDF]
Tahsin F+11 more
europepmc +1 more source