Results 31 to 40 of about 407,861 (266)
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
FEBS Letters, EarlyView.α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley +1 more source
Hierarchical Systems in Open Clusters [PDF]
, 1997 14 pages, LaTeX, 6 ps figures. To be published in: Visual Double Stars: Formation, Dynamics and Evolutionary Tracks, eds. J. A. Docobo, A. Elipe, and H. McAlister, (KAP:ASSL Series)
Peter P. Eggleton +3 more
openaire +4 more sources
The open cluster Berkeley 53 [PDF]
Astronomische Nachrichten, 2009 AbstractWe present a photometric study of the neglected open cluster Berkeley 53. We derived its fundamental parameters, such as the age, the interstellar reddening, and the distance from the Sun, based on BV photometry combined with near‐infrared JHKS data.
Boyko Mihov +2 more
openaire +3 more sources
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Pulsatin stars in open clusters [PDF]
Communications in Asteroseismology, 2007 We report studies that are carried out with the aim of searching for and studying short-period variable stars in northern open clusters. The background for these studies is described along with the results that have been obtained up to now.
Arentoft, T. +4 more
openaire +3 more sources
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Open clusters and the galactic disk [PDF]
Astronomische Nachrichten, 2010 AbstractIt is textbook knowledge that open clusters are conspicuous members of the thin disk of our Galaxy, but their role as contributors to the stellar population of the disk was regarded as minor. Starting from a homogenous stellar sky survey, the ASCC‐2.5, we revisited the population of open clusters in the solar neighbourhood from scratch.
Nina V. Kharchenko +6 more
openaire +5 more sources
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Molecular Oncology, EarlyView.The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens +8 more
wiley +1 more source