Results 61 to 70 of about 443,609 (315)
FEBS Letters, EarlyView.The amyloid world hypothesis of the origin‐of‐life posits that the first functional polymers on the early Earth were structurally stable cross‐β‐sheet‐based peptide amyloids capable of Darwinian‐like evolution. Peptide amyloids display self‐replication and information transfer, as well as catalytic, adaptive, and evolutive properties.
Carl Peter J. Maury
wiley +1 more source
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
Hierarchical Systems in Open Clusters [PDF]
, 1997 14 pages, LaTeX, 6 ps figures. To be published in: Visual Double Stars: Formation, Dynamics and Evolutionary Tracks, eds. J. A. Docobo, A. Elipe, and H. McAlister, (KAP:ASSL Series)
Peter P. Eggleton +3 more
openaire +4 more sources
Open clusters and the galactic disk [PDF]
Astronomische Nachrichten, 2010 AbstractIt is textbook knowledge that open clusters are conspicuous members of the thin disk of our Galaxy, but their role as contributors to the stellar population of the disk was regarded as minor. Starting from a homogenous stellar sky survey, the ASCC‐2.5, we revisited the population of open clusters in the solar neighbourhood from scratch.
Nina V. Kharchenko +6 more
openaire +5 more sources
FEBS Letters, EarlyView.Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria +3 more
wiley +1 more source
The orbits of open clusters in the Galaxy [PDF]
Monthly Notices of the Royal Astronomical Society, 2009 We present and analyze kinematics and orbits for a sample of 488 open clusters in the Galaxy. The velocity ellipsoid for our present sample is derived as ($ _{U}$, $ _{V}$, $ _{W})$=$(28.7$, 15.8, 11.0) km s$^{-1}$ which represents a young thin disc population. We also confirm that the velocity dispersions increase with the age of cluster subsample.
Jun Ma, Zhenyu Wu, Xu Zhou, Cuihua Du
openaire +4 more sources
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
NGC 2180: A disrupting open cluster? [PDF]
Astronomy & Astrophysics, 2004 9 pages, 8 ...
Charles Jose Bonatto +2 more
openaire +2 more sources
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
FEBS Letters, EarlyView.The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen +2 more
wiley +1 more source
Journal of Open Innovation: Technology, Market and Complexity, 2020 The purpose of this paper is to provide an insight into the barriers faced by clusters as open innovation intermediaries. Literature review and an empirical study were performed, involving a nation-wide survey, case studies, and in-depth interviews with ...
Marita McPhillips
doaj +1 more source