Results 81 to 90 of about 458,301 (316)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Basic Kinematics of the Galactic Disk from Open Cluster Data

Open Astronomy, 2016
The kinematic parameters of the Galactic disk are redetermined based on open-cluster data. It is shown that the Bottlinger-Oort model of pure circular rotation can be confidently used to describe the observed motions of disk objects at least out to ...
Loktin A. V., Popova M. E.
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Stellar Variability toward the Galactic Open Cluster NGC 7209

The Astrophysical Journal
We present the analysis of stellar variability in an open cluster NGC 7209 using optical V -band CCD photometric observations. Out of 4499 stars in our study, we detected 284 candidate variables, including one identified previously.
Dorothy M. Mwanzia, Sneh Lata, W. P. Chen, Soumen Mondal, Geoffrey Okeng’o, John Buers, Samrat Ghosh, Athul Dileep, Arjav Jain, Alisher S. Hojaev, Santosh Joshi   +10 more
doaj   +1 more source

Vilnius Multicolor CCD Photometry of the Open Cluster NGC 752

Open Astronomy, 2011
We have performed multicolor CCD observations of the central area of NGC 752 to search for faint, low-mass members of this open cluster. Four 12’ x 12’ fields were taken on the 1.8 m Vatican Advanced Technology Telescope (Mt.
Bartašiūtė S., Janusz R., Boyle R. P., Philip A. G. Davis   +3 more
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

β,β-Isomer of Open-Wells–Dawson Polyoxometalate Containing a Tetra-Iron(III) Hydroxide Cluster: [{Fe4(H2O)(OH)5}(β,β-Si2W18O66)]9−

Inorganics, 2016
The β,β-isomer of open-Wells–Dawson polyoxometalate (POM) containing a tetra-iron(III) cluster, K9[{Fe4(H2O)(OH)5}(β,β-Si2W18O66)]·17H2O (potassium salt of β,β-Fe4-open), was synthesized by reacting Na9H[A-β-SiW9O34]·23H2O with FeCl3·6H2O at pH 3, and ...
Satoshi Matsunaga, Eriko Miyamae, Yusuke Inoue, Kenji Nomiya   +3 more
doaj   +1 more source

Extended Main-sequence Turnoff as a Common Feature of Milky Way Open Clusters [PDF]

, 2018
G. Cordoni, A.P. Milone, A. F. Marino, M. Di Criscienzo, F. D'Antona, A. Dotter, E. P. Lagioia, M. Tailo, G. Cordoni, A.P. Milone, A. F. Marino, M. Di Criscienzo, F. D'Antona, A. Dotter, E. P. Lagioia, M. Tailo   +15 more
openalex   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source