Results 101 to 110 of about 4,555,706 (361)

Analisis Sensitivitas Pada Pipa Besi Cor Dengan Retakan Kearah Melingkar Pipa [PDF]

, 2009
Effect of pressure in the pipe at the rate of leakage from the pipe which is one of the main factors affecting the leak still not adequately understood.
Gunawan, G. (Gunawan)
core   +1 more source

Finite element analysis of fretting crack propagation

, 2011
In this work, the finite elements method (FEM) is used to analyse the growth of fretting cracks. FEM can be favourably used to extract the stress intensity factors in mixed mode, a typical situation for cracks growing in the vicinity of a fretting ...
Basseville, Stéphanie, Proudhon, Henry
core   +3 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Identification of open cracks using wavelet analysis [PDF]

, 2010
Damage detection in flexural members by wavelet analysis involves certain important factors such as the choice of wavelet function, the effects of windowing and the effects of masking due to the presence of noise during measurement. A numerical study has
Basu, Biswajit, O'Connor, Alan J., Pakrashi, Vikram   +2 more
core  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Investigation of an Open Loop Resonator for Crack Detection

Engineering Proceedings
Structural Health Monitoring (SHM) of composite systems is challenging due to multiple factors unique to composites. Early detection of any defects in composites is essential to ensure structural integrity and prevent catastrophic failure.
Adithya Krishna Menon, C. B. Abhinav, Sreedevi K. Menon, M. P. Hariprasad   +3 more
doaj   +1 more source

The mechanics of delamination in fiber-reinforced composite materials. Part 1: Stress singularities and solution structure [PDF]

The fundamental mechanics of delamination in fiber composite laminates is studied. Mathematical formulation of the problem is based on laminate anisotropic elasticity theory and interlaminar fracture mechanics concepts.
Choi, I., Wang, S. S.
core   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Implementation of a Matrix Crack Spacing Parameter in a Continuum Damage Mechanics Finite Element Model [PDF]

Continuum Damage Mechanics (CDM) based progressive damage and failure analysis (PDFA) methods have demonstrated success in a variety of finite element analysis (FEA) implementations.
Bergan, Andrew, Hyder, Imran, Justusson, Brian P., Leone, Frank A., Schaefer, Joseph D., Wanthal, Steven   +5 more
core   +1 more source

Quasi-static cracks and minimal energy surfaces [PDF]

, 1998
We compare the roughness of minimal energy(ME) surfaces and scalar ``quasi-static'' fracture surfaces(SQF). Two dimensional ME and SQF surfaces have the same roughness scaling, w sim L^zeta (L is system size) with zeta = 2/3.
A. A. Middleton, A. Hansen, A. Hansen, A. Kelly, A. Omeltchenko, D. Fisher, E. Bouchard, E. T. Seppala, J. Kertesz, K. J. Måløy, M. J. Alava, M. J. Alava, M. Kardar, P. Daguier, P. M. Duxbury, P. M. Duxbury, S. J. Zhou, S. Ramanathan, T. Yamauchi, V. I. Räisänen, V. Y. Milman, V. Y. Milman, X. P. Xu   +22 more
core   +2 more sources