Results 61 to 70 of about 4,555,706 (361)

Finite-Element Analysis of Shear-off Failure of Keyed Dry Joints in Precast Concrete Segmental Bridges [PDF]

, 2014
This article has been made available through the Brunel Open Access Publishing Fund.The structural behaviour of precast concrete segmental bridges is largely dependent on the behaviour of the joints between segments.
Giulio Alfano, M. Asce, Ph. D, Ph. D, Rabee Shamass, Xiangming Zhou   +5 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

The dual role of martensitic transformation in fatigue crack growth

Proceedings of the National Academy of Sciences of the United States of America, 2022
Significance About 90% of all mechanical service failures are caused by fatigue. Avoiding fatigue failure requires addressing the wide knowledge gap regarding the micromechanical processes governing damage under cyclic loading, which may be fundamentally
Xiaogang Wang, Chenghuan Liu, Binhan Sun, D. Ponge, Chao Jiang, D. Raabe   +5 more
semanticscholar   +1 more source

Research on TBM Cutterhead Crack Damage and Fatigue Reliability

Applied Sciences, 2021
The cutterhead of a tunnel-boring machine (TBM) is the main weighted part in the process of tunneling and bears loadings in different directions. A fatigue failure of a cutterhead would severely affect the construction progress and safety.
Ding Wang, Chuanyong Qu
doaj   +1 more source

Stress corrosion cracking in Al-Zn-Mg-Cu aluminum alloys in saline environments [PDF]

, 2012
Copyright 2013 ASM International. This paper was published in Metallurgical and Materials Transactions A, 44A(3), 1230 - 1253, and is made available as an electronic reprint with the permission of ASM International.
A. Berzin, A. Kolics, A. Turnbull, A.H. Le, A.H. Le, A.J. McEvily, A.K. Vasudevan, A.S. Tetelman, B. Jegdic, B. Sakar, B.J. Connelly, B.J. Connelly, C.A. Loto, C.M. Liao, D.J. Sullivan, D.M. Drazic, E.A. Starke, F.E. Watkinson, F.P. Ford, F.S. Lin, G. M. Scamans, G.A. Young, G.A. Young, G.M. Scamans, G.M. Scamans, H. Gruhl, H. Kim, H.F. Jong de, J. Onoro, J. Onoro, J. Robinson, J. Zhang, J.K. Park, J.P. Nordin, J.R. Scully, K. Kitamura, K. Komai, K.G. Kent, K.P. Wong, K.R. Cooper, K.R. Cooper, K.R. Cooper, L. Tomcsanyi, L.H. Chambers, L.P. Huang, M. Abe, M. Cook, M. Landkof, M. Metikos-Hukovic, M. Watanabe, M.O. Speidel, M.V. Hyatt, N. J. Henry Holroyd, N. Lampeas, N.J.H. Holroyd, N.J.H. Holroyd, N.J.H. Holroyd, O.D. Sherby, P. Martin, P.M. Natishan, R. Hermann, R.C. Doward, R.S. Pathania, R.T. Foley, R.T. Foley, S. Lee, S. Mostovoy, S. Ohsaki, S. Ohsaki, S. Osaki, S. Pyun, S. Pyun, T. Ishikawa, T. Magnin, T. Ohnishi, T. Oka, T.H. Nguyen, T.H. Nguyen, T.H. Sanders, W. Gruhl, Y. Choi, Z.A. Foroulis   +81 more
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Influence of Grain Boundary on the Fatigue Crack Growth of 7050-T7451 Aluminum Alloy Based on Small Time Scale Method

Advances in Materials Science and Engineering, 2016
Based on the small time scale method, the influence of grain boundary on the fatigue crack growth of 7050-T7451 has been investigated. The interaction between fatigue crack and grain boundary was investigated by in situ SEM testing.
Weihan Wang, Weifang Zhang, Hongxun Wang, Xiaoliang Fang, Xiaobei Liang   +4 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Fatigue crack growth analysis on square prismatic with embedded cracks under tension loading

Journal of Mechanical Engineering and Sciences, 2017
One of the most important issues yet to be overcome by engineers is the integrity and reliability of engineering structures. This is to ensure the safety of the engineering structure is at the greatest since the catastrophic failures usually occur due to
M.S. Shaari, A.K. Ariffin, Akiyuki Takahashi, S. Abdullah, Masanori Kikuchi, M.R.M. Akramin   +5 more
doaj   +1 more source

The effect of low-cycle fatigue on evolution of fracture mechanics parameters in residual stress field caused by cold hole expansion [PDF]

Fracture and Structural Integrity, 2019
Localized displacement measurements based on electronic speckle-pattern interferometry are used to obtain crack mouth opening displacement (CMOD), stress intensity factor (SIF) and T-stress values during crack growth around cold-expanded holes.
Yu. G. Matvienko, V.S. Pisarev, S. I. Eleonsky   +2 more
doaj   +1 more source