Results 161 to 170 of about 35,965,782 (395)

Open research data: Report to the Australian National Data Service (ANDS) [PDF]

open access: yes
Main points Research data are an asset we have been building for decades, through billions of dollars of public investment in research annually. The information and communication technology (ICT) revolution presents an unprecedented opportunity to ...
John Houghton, Nicholas Gruen
core  

DBpedia: A Nucleus for a Web of Open Data

open access: yesISWC/ASWC, 2007
S. Auer   +5 more
semanticscholar   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

The effectiveness of the Fracture Risk Evaluation Model (FREM) in predicting major osteoporotic fractures and hip fractures: A register-based cohort study

open access: yesBone Reports, 2020
Michael Kriegbaum Skjødt   +6 more
doaj   +1 more source

Improving the Performance of Open-Set Recognition with Generated Fake Data [PDF]

open access: gold, 2023
András Pál Halász   +4 more
openalex   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Targeting molecular quantum memory with embedded error correction. Open data set

open access: green, 2021
Selena J. Lockyer   +7 more
openalex   +1 more source

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