Results 171 to 180 of about 11,640,166 (343)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Open Data [PDF]

open access: yes, 2020
Tim Davies, Ania Calderon
openaire   +3 more sources

Open Source & Open Data

open access: yes, 2019
Proyectos de Código Abierto (Open Source) y de Acceso Abierto (Open Access) han definido y siguen dando forma a grandes desarrollos en la ciencia fundamental y las tecnologías de la información.Desde hace mucho tiempo, pero más aun hoy en día, empresas científicas y colaboraciones académicas impulsan un basto set de proyectos Open Source en términos de
openaire   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Open Data In Neurophysiology: Advancements, Solutions & Challenges. [PDF]

open access: yeseNeuro
Gillon CJ   +7 more
europepmc   +1 more source

An open data collection of 3D tool and equipment models for neonatology

open access: gold
Serena Bardelli   +4 more
openalex   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Disaster, Participatory Science, and Infrastructure

open access: yesCitizen Science: Theory and Practice, 2022
Shannon Dosemagen   +3 more
doaj   +1 more source

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