Results 191 to 200 of about 11,640,166 (343)

AgTC and AgETL: open-source tools to enhance data collection and management for plant science research [PDF]

Luis Vargas-Rojas, To‐Chia Ting, Katherine M. Rainey, Matthew Reynolds, Diane Wang   +4 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

The rise of open data practices among bioscientists at the University of Edinburgh. [PDF]

PLoS One
Deeb H, Creasey S, de Ugarte DL, Strevens G, Usman T, Wong HY, Kutzer MAM, Wilson E, Zieliński T, Millar AJ.   +9 more
europepmc   +1 more source

Open Tools for NEON Data: Lessons from Open Code Development by NEON Scientists and the NEON User Community

, 2020
Claire Lunch, Christine Laney, Megan A. Jones, David Durden   +3 more
openalex   +1 more source

Development of an Algorithm to Analyze Vacancies in the Labor Market Based on Open-Source Data

, 2022
Oksana А. Khokhlova, A. N. Khokhlova, A.Ts. Choyzhalsanova   +2 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

State of Open Data survey 2017

, 2017
Nature Research, Mathias Astell, Dan Penny, Jon Treadway, Briony Fane   +4 more
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Explainable Transformer-Based Modelling for Pathogen-Oriented Food Safety Inspection Grade Prediction Using New York State Open Data. [PDF]

Foods
Sari OF, Bader-El-Den M, Ince V.
europepmc   +1 more source

Prospects for open data in New Zealand

, 2007
Peter Suber
openalex   +1 more source