Results 231 to 240 of about 11,640,166 (343)

Forecasting Traffic Congestion in Road Network Sections Based on Open Source Data (In Russ.)

Aleksandr S. Morozov, Polina Krupenina, Tatiana I. Baltyzhakova   +2 more
openalex   +1 more source

Ketersediaan Lahan Pemakaman Saat Pandemi Covid-19 (Studi Kasus: Kota Surakarta Dengan Pemanfaatan Open Data)

, 2021
Brian Pradana, Bagus Nuari Priambudi, Muhammad Indra Hadi Wijaya   +2 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

MDRepo-an open data warehouse for community-contributed molecular dynamics simulations of proteins. [PDF]

Nucleic Acids Res
Roy A, Ward E, Choi I, Cosi M, Edgin T, Hughes TS, Islam MS, Khan AM, Kolekar A, Rayl M, Robinson I, Sarando P, Skidmore E, Swetnam TL, Wall M, Xu Z, Yung ML, Merchant N, Wheeler TJ.   +18 more
europepmc   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Modelling the high-voltage grid using open data for Europe and beyond. [PDF]

Sci Data
Xiong B, Fioriti D, Neumann F, Riepin I, Brown T.   +4 more
europepmc   +1 more source

Estimating On-road Transportation Carbon Emissions from Open Data of Road Network and Origin-destination Flow Data [PDF]

Jinwei Zeng, Yu Liu, Jingtao Ding, Jian Yuan, Yong Li   +4 more
openalex   +1 more source

Linking social, open, and enterprise data

Davies, John, Duke, Alistair, Glaser, Hugh, Omitola, Tope, Shadbolt, Nigel   +4 more
core   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source