Results 291 to 300 of about 11,122,566 (354)

Data-driven type checking in open domain question answering

, 2006
Stefan Schlobach, David Ahn, Maarten de Rijke, Valentin Jijkoun   +3 more
openalex   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Open instrumentation, like open data, is key to reproducible science. Yet, without incentives it won't thrive. [PDF]

Philos Trans A Math Phys Eng Sci
Stirling J.
europepmc   +1 more source

A study concerning evaluation of open space planning for reduction of heat island based on Landsat data

, 2006
Teruaki Irie
openalex   +2 more sources

The roles and applications of extracellular vesicles in cancer

Molecular Oncology, EarlyView.
Extracellular vesicles (EVs) are minute versions of cells limited by a lipid bilayer containing cytoplasm from the cell that releases them, but without a nucleus and thus unable to self‐reproduce. EVs contain multiple molecules (proteins, lipids, glycans, and nucleic acids) they can induce complex responses in cells.
Clotilde Théry, Daniel Louvard
wiley   +1 more source

Exploring Freely Available Data Tools to Support Open Data and Open Science. [PDF]

J Hosp Librariansh
Hislop C, Farrier KP, Roth E.
europepmc   +1 more source

The PAPILLON project: cooperatively building a multilingual lexical data-base to derive open source dictionaries and lexicons

, 2002
Christian Boitet, Mathieu Mangeot, Gilles Sérasset   +2 more
openalex   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Correction: Improving accessibility to radiotherapy services in Cali, Colombia: cross-sectional equity analyses using open data and big data travel times from 2020. [PDF]

Int J Equity Health
Cuervo LG, Villamizar CJ, Cuervo D, Zapata P, Ospina MB, Valencia SM, Polo A, Suarez A, Bula MO, Miranda JJ, Millan G, Cuervo DE, Owens NJ, Piquero F, Hatcher-Roberts J, Paredes GD, Navarro MF, Minotta IL, Palta C, Martinez-Herrera E, Jaramillo C, AMORE Project Collaboration.   +21 more
europepmc   +2 more sources

Open-access Repositories—Taking Data Out of the Hands of the Protagonists

, 2006
Tony Fletcher
openalex   +1 more source