Results 31 to 40 of about 19,781,428 (312)

Study on Process Event of a Meteorological Drought Comprehensive Index

open access: yesGaoyuan qixiang
In order to understand the long-term evolution of meteorological drought in Chongqing, the localized revised meteorological drought comprehensive index (RMCI) of 34 national stations in Chongqing from 1960 to 2022 was used in conjunction with local ...
Chi ZHANG   +4 more
doaj   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

Two heuristic algorithms for location-inventory-routing models involving two warehouses within multi-echelon supply chain networks

open access: yesScientific Reports
In supply chain management, the location of facilities, inventory control, and vehicle routing are three key components. This paper incorporates a two-warehouse inventory system into the location- inventory-routing problems (LIRPs) and develops LIRP ...
Zhuo Dai, Yefu Zhou, Bibhas Chandra Giri
doaj   +1 more source

Informal financial education and consumer financial capability: The mediating role of financial knowledge

open access: yesFrontiers in Psychology, 2022
With the development of the economy, family wealth continues to accumulate, and more and more consumers participate in financial management affairs. As an important way to improve financial knowledge, informal financial education is vital to consumer ...
Fuzhong Chen   +3 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Interface optimization and process scale-up study of electrocatalytic reduction of CO2 to CO in acidic flow electrolyzers

open access: yes能源环境保护
The electrocatalytic carbon dioxide reduction reaction (eCO2RR) powered by renewable energy can convert CO2 into high-value chemicals and fuels. It is a viable solution to address the sharp increase in atmospheric CO2 concentration and global warming ...
Feiyu MA   +6 more
doaj   +1 more source

Cross-Border E-Commerce Pilot Zones and Greenfield Foreign Investment: Evidence from China

open access: yesMathematics
Cross-border e-commerce, as a vital form of digital trade, is emerging as a new engine for corporate internationalization. This study employs China’s cross-border e-commerce pilot zones (established since 2015) as a quasi-natural experiment to ...
Jianyu Jin, Tianxiang Song
doaj   +1 more source

Monetary targets and indicators in an open economy: reflections on the Canadian experience

open access: yesPSL Quarterly Review, 2014
The choice of the appropriate target and indicator in monetary policy has been the subject of considerable debate in recent years, however, analysis has tended to be theoretical in nature and confined to the case of a closed economy.
J.E. PESANDO, L.B. SMITH
doaj   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

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