Results 91 to 100 of about 1,948,813 (330)

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

open access: yesFEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito   +3 more
wiley   +1 more source

Cost-Savings Achieved in Two Semesters Through the Adoption of Open Educational Resources

open access: yesInternational Review of Research in Open and Distributed Learning, 2014
Textbooks represent a significant portion of the overall cost of higher education in the United States. The burden of these costs is typically shouldered by students, those who support them, and the taxpayers who fund the grants and student loans which ...
John Levi Hilton III   +3 more
doaj  

Automatic generation of audio content for open learning resources [PDF]

open access: yes, 2009
This paper describes how digital talking books (DTBs) with embedded functionality for learners can be generated from content structured according to the OU OpenLearn schema.
Brasher, Andrew, McAndrew, Patrick
core   +2 more sources

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

Open Content: when is it effective educationally? [PDF]

open access: yes, 2007
Open Educational Resources (OERs) are often seen as a subset of Open Content. This raises the question of what characterises OERs and distinguishes it from other types of Open Content? And if the content is deemed educational then what makes it effective
Lane, Andrew
core  

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

open access: yesFEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

A Path Analysis of Educator Perceptions of Open Educational Resources Using the Technology Acceptance Model

open access: yesInternational Review of Research in Open and Distributed Learning, 2014
Open educational resources (OER) are making their way into a variety of educational contexts from formal lesson planning to just in time learning. Educators and training professionals have been recognized as an important audience for these materials. The
Hope Kelly
doaj  

Collaborative Development of Open Educational Resources for Open and Distance Learning [PDF]

open access: yes, 2012
Open and distance learning (ODL) is mostly characterised by the up front development of self study educational resources that have to be paid for over time through use with larger student cohorts (typically in the hundreds per annum) than for ...
Andy Lane   +2 more
core   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

open access: yesFEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima   +4 more
wiley   +1 more source

Measuring Use and Creation of Open Educational Resources in Higher Education

open access: yesInternational Review of Research in Open and Distributed Learning, 2013
The open educational resources initiative has been underway for over a decade now and higher education institutions are slowly adopting open educational resources (OER).
Ross McKerlich, Cindy Ives, Rory McGreal
doaj  

Home - About - Disclaimer - Privacy