Results 121 to 130 of about 11,269 (263)

Circulating Tumor DNA Assessment of Disease Response in Large B-Cell Lymphoma: Lisocabtagene Maraleucel Versus Autologous Stem Cell Transplantation Standard Therapy. [PDF]

J Clin Oncol
Stepan L, Ansari S, Abramson JS, Okal A, Dell'Aringa J, Thompson EG, Crotta A, Chow VA, Kamdar M, Solomon SR, Johnston PB, Glass B, Mutsaers P, Arnason J, Mielke S, Shadman M, Hernandez-Ilizaliturri F, Izutsu K, Bachanova V, Ibrahimi S, Chabon JJ, Kurtz DM, Alizadeh AA, Peiser L.   +23 more
europepmc   +1 more source

Redefining CHI3L1: Therapeutic Opportunities at the Crossroads of Immune Suppression and Disease Progression

Medicinal Research Reviews, EarlyView.
ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu, Saurabh Upadhyay, Moustafa T. Gabr   +2 more
wiley   +1 more source

Critical uncertainties in preclinical research: Navigating trust, technology, and ethics. [PDF]

Neurosci Appl
Heinla I, Voikar V, Gates H, Bains RS, Wells S, Mandillo S, Čater M, Kukk K, Lewejohann L, Hrnčić D, Duarte-Domingues D, Villiger P, Restivo L, Hölter SM.   +13 more
europepmc   +1 more source

The influence of team variables during the decision-making porcess of open foresight

, 2020
Open Foresight is a collaborative approach between two or more firms with the aim to anticipate future trends and changes in the company environment. Stakeholders and individuals from inside and outside the firm come together to share knowledge to reduce uncertainty about future events.
openaire   +1 more source

Interplanetary frontiers: terraforming from an invasion science perspective

Oikos, EarlyView.
The pursuit of a multi‐planetary existence represents one of humanity's greatest frontiers. If applied justly, it offers an opportunity to extend its civilization's lifespan amid escalating sustainability crises on Earth. One approach increasingly gaining traction is terraforming, a hitherto theoretical ecological and evolutionary experiment revolving ...
Teun Everts, Ronaldo Sousa, Phillip J. Haubrock   +2 more
wiley   +1 more source

Horizon Scanning for Medical Technologies: Methodological Framework Development Study of the Medical Innovation Scanning Techniques (MIST) Framework. [PDF]

J Med Internet Res
Garcia Gonzalez-Moral S, Mkwashi A, Beyer FR, Craig D.   +3 more
europepmc   +1 more source

Mechanisms and impacts of future plant invasions: research agendas and management needs under disruptive social‐ecological change scenarios

Oikos, EarlyView.
No‐analogue futures are characteristic of the Anthropocene, but how global change, and societies' responses, will affect plant invasions remains unclear. Conducting research now to address future needs is crucial for guiding invasion management and policy.
Jennifer L. Bufford, Angela J. Brandt, Rowan Sprague, Christopher E. Buddenhagen, Richard P. Duncan, Nichola Harcourt, Philip E. Hulme, Hao Ran Lai, Kate G. McAlpine, Chris McGrannachan, Fiona J. Thomson, Vincent van Uitregt, Duane A. Peltzer   +12 more
wiley   +1 more source

Horizon scanning at EMA: preparing for the medicines of the future. [PDF]

Front Med (Lausanne)
Correia PD, Cordo' V, Blanquie O, Tognana E, Balourdas DI, Ziogas C, Ehmann F.   +6 more
europepmc   +1 more source

AI‐Ready Bureaucracies? Assessing Capacity‐Building Approaches in European National AI Strategies

Public Administration and Development, EarlyView.
ABSTRACT The global expansion of Artificial Intelligence (AI) strategies is reshaping expectations about state capacity, yet the role of civil servants in this transition remains insufficiently theorized. This study examines how EU Member States address the civil service workforce in their national AI strategies, employing content and cluster analysis ...
Manuel Pedro Rodríguez Bolívar, Sergio Medina‐Bernabé, J. Ignacio Criado   +2 more
wiley   +1 more source

Clarifying Public Policy for Stronger Public Administration in Development

Public Administration and Development, EarlyView.
ABSTRACT Public policy is ubiquitous, yet its meaning is often unclear. This ambiguity is not just conceptual. Because policy work is a large part of what public administrations do, how we define policy shapes how we structure and organize our administrative mechanisms.
Matt Andrews
wiley   +1 more source