Results 251 to 260 of about 160,008 (304)

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

Advanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu, Wen Geng, Zhi Du, Yifan Du, Di Wu, Bide Tong, Huaizhen Liang, Xingyu Zhou, Zixuan Ou, Junyu Wei, Kun Wang, Yu Song, Wenbin Hua, Yan Xu, Wencan Ke, Bingjin Wang, Cao Yang   +16 more
wiley   +1 more source

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

Advanced Science, EarlyView.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li, Yuying Zhang, Jingjing Wang, Qianqian Zhang, Hailiang Sun, Fanhua Wei   +5 more
wiley   +1 more source

Jurors in the Material World: Putting Tort Verdicts in Their Social Context [PDF]

, 2008
Hensler, Deborah R.
core   +1 more source

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Prognostic indicators for open globe injury

Clinical & Experimental Ophthalmology, 2006
AbstractBackground:  The purpose of the study is to identify factors predictive of outcome after open globe injury in 273 patients admitted to the Royal Brisbane Hospital, Queensland, Australia between 1992 and 2003.Methods:  Data were collected retrospectively regarding demographic and geographical factors, injury circumstances, initial visual acuity (
Rofail, Marc, Lee, Graham A., O'Rourke, Peter   +2 more
openaire   +5 more sources

Endophthalmitis following open-globe injuries

Current Opinion in Ophthalmology, 1998
Endophthalmitis following open-globe injuries is caused by a specific range of microorganisms, of which Bacillus sp. and coagulase-negative Staphylococcus are the most frequent. Risk factors include the presence of an intraocular foreign body, injury inflicted by organic material, delay in surgery, and the type of wound involved.
Duch Samper, Antonio Miguel, Chaqués-Alepuz, Vicente, Menezo, Jose Luis, Hurtado Sarrió, Mercedes   +3 more
openaire   +3 more sources

Wood-Related Open-Globe Injuries

Journal of VitreoRetinal Diseases, 2020
Purpose: This work evaluates the clinical characteristics, visual outcomes, and complications of patients treated for open-globe injuries (OGIs) caused by wooden objects. Methods: A retrospective review of medical records was conducted on patients presenting to a tertiary trauma center with an OGI between January 2005 and December 2017. Medical records
Tyler, Pfister, Carisa, Bohnak, Shriji, Patel   +2 more
openaire   +2 more sources

Open globe injuries in children

Graefe's Archive for Clinical and Experimental Ophthalmology, 2000
Eye injuries are the leading cause of monocular blindness in children. At present, however, only limited follow-up studies exist.The files of 38 consecutive patients aged 16 years or younger who had been treated for open globe injuries were examined. The type of injury was classified and the severity of injury was categorized in four grades.Our series ...
C, Jandeck, U, Kellner, N, Bornfeld, M H, Foerster   +3 more
openaire   +2 more sources

Open globe injuries in children

Journal of American Association for Pediatric Ophthalmology and Strabismus, 1998
A retrospective review of open globe injuries in children was performed to identify the common types of injury and to correlate features of the injuries and surgical management with visual prognosis.The hospital records of 70 patients were reviewed to determine demographic data, the nature and location of the injuries, the anatomic and functional ...
K, Rostomian, A B, Thach, A, Isfahani, A, Pakkar, R, Pakkar, M, Borchert   +5 more
openaire   +2 more sources

Wartime open globe eye injuries

Graefe's Archive for Clinical and Experimental Ophthalmology, 2009
Open globe injuries are the most serious eye injuries in war as in peace time. The purpose of this study is to analyze wartime open globe eye injuries in 72 patients treated at the Department of Ophthalmology, Clinical Hospital of Split from July 1991 to April 1993, during the intensive war in Croatia and Bosnia and Herzegovina, and to evaluate crucial
Pleština-Borjan, Ivna, Medvidović-Grubišić, Marija, Žuljan, Igor, Lakoš, Venera, Miljak, Snježana, Marković, Irena, Ivanišević, Milan   +6 more
openaire   +2 more sources

Enucleation for Open Globe Injury

American Journal of Ophthalmology, 2009
To report the experience of enucleation after open globe at an ophthalmic trauma referral center.Retrospective, observational study.In an ophthalmic trauma referral center the charts of all patients having suffered an open globe injury between January 1, 2000 and June 30, 2007 were reviewed.
Aaron, Savar, Michael T, Andreoli, Carolyn E, Kloek, Christopher M, Andreoli   +3 more
openaire   +2 more sources