Results 41 to 50 of about 841,980 (298)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
THE ROLE OF DATA OPENING IN CREATING ADDED VALUE [PDF]
Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2017 Increasing the use of information and communication technology in all sectors of activity has generated the emergence of open government concepts and open government data, which, as they are implemented in practice, reveal a new direction for research ...
CĂTĂLIN FLORIN ZETI +3 more
doaj
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Internet Voting for Policy Proposals: Amplifying Open Government in Chile and Colombia
, 2023 EnglishThis paper investigates the impact of internet voting for draft policy proposals in the framework of Open Government Partnership, on the whole ecosystem of open government in Chile and Colombia. The research objective is, to identify the impact of
Laureda, Eduardo Astudillo +3 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Promoting Open Government Partnership: Insights From La Libertad, Peru
Jurnal PolitiqueThis study aims to analyze the open government of La Libertad, Peru. La Libertad has a leading role as the only local government pilot model by the Open Government Partnership in the country.
Rizki Erdayani +2 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Carbon Balance and ManagementThe rapid increase in municipal solid waste (MSW) generation across urban centers in Pakistan, combined with insufficient waste management infrastructure, presents a significant environmental and public health challenge.
Bibi Ilmas +3 more
doaj +1 more source