Mepce Restrains Ferroptosis in Prostate Cancer Through 7SK–P‐TEFb Pause Control
Genome‐wide CRISPR screening identifies MEPCE as a pause‐control regulator that restrains ferroptosis in prostate cancer. MEPCE loss releases P‐TEFb/CDK9 from 7SK snRNP control, enhances RNAPII Ser2 phosphorylation, and accelerates NRF2‐HMOX1‐driven labile iron accumulation and lipid peroxidation, revealing a transcriptional kinetic gate that lowers ...
Tongtong Zhang +9 more
wiley +1 more source
Spatial access to inpatient mental health services in Kerala, India: a Geospatial Information System-based travel-time isochrone analysis. [PDF]
Varughese DT, Thomas JE, Paulose JK.
europepmc +1 more source
F7 Drives Gastric Cancer Metastasis Through Anoikis Resistance and Tumor Microenvironment Remodeling
ABSTRACT Coagulation factor VII (F7) has been implicated in tumor progression; however, its role in gastric cancer metastasis and immune evasion remains incompletely understood. In this study, we identified F7 as a clinically relevant driver of gastric cancer.
Lei Gao +9 more
wiley +1 more source
Comparison of Open vs. Mini-Open Approach in Treatment of Acute Acromioclavicular Joint Dislocation Using a Suspensory Fixation System: A Retrospective Cohort Study. [PDF]
Glavaš Weinberger D +9 more
europepmc +1 more source
From Sourcing to End‐of‐Life: Sustainability Challenges and Opportunities in Organic Bioelectronics
Organic bioelectronics bridges biology and electronics using organic mixed ionic/electronic conductors. This Perspective addresses sustainability across the full lifecycle of organic bioelectronic materials and devices, offering a framework to guide material sourcing, synthesis, fabrication, application, and end‐of‐life strategies toward bioelectronic ...
Gwennaël Dufil +3 more
wiley +1 more source
Correction: Exclusion of the left atrial appendage in Chinese population with perclip system: 1-year follow-up outcome results from a prospective, multi-center, open-label, single-arm device trial. [PDF]
Li H +16 more
europepmc +1 more source
This review explores emerging 2D materials beyond graphene, including graphdiyne, phosphorene, borophene, siloxene, MBene, antimonene, and germanene for Li/Na–S batteries. It analyzes their roles as sulfur hosts, metallic anode protectors, separators, and electrolyte fillers, emphasizing polysulfide suppression, dendrite inhibition, and interfacial ...
Naveen Kumar T. R +7 more
wiley +1 more source
An open-source BLDC motor test bed utilizing ESC telemetry for cost-effective educational laboratories. [PDF]
Kurniawan UTY, Faridah, Sunarno.
europepmc +1 more source

