Results 51 to 60 of about 1,366,220 (285)

CellAnimation: an open source MATLAB framework for microscopy assays [PDF]

Bioinformatics, 2011
AbstractMotivation: Advances in microscopy technology have led to the creation of high-throughput microscopes that are capable of generating several hundred gigabytes of images in a few days. Analyzing such wealth of data manually is nearly impossible and requires an automated approach.
Walter, Georgescu, John P, Wikswo, Vito, Quaranta   +2 more
openaire   +2 more sources

The miEye: Bench-top super-resolution microscope with cost-effective equipment

HardwareX, 2022
Commercial super-resolution (SR) imaging systems require a high budget, while current more affordable open source microscopy systems lack modularity and sometimes are too complex or lack reliability.
Mohammad Nour Alsamsam, Aurimas Kopūstas, Meda Jurevičiūtė, Marijonas Tutkus   +3 more
doaj   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

MicroMator: Open and Flexible Software for Reactive Microscopy [PDF]

, 2021
AbstractMicroscopy image analysis has recently made enormous progress both in terms of accuracy and speed thanks to machine learning methods. This greatly facilitates the online adaptation of microscopy experimental plans using real-time information of the observed systems and their environments. Here we report MicroMator, an open and flexible software
Zachary R Fox, Steven Fletcher, Achille Fraisse, Chetan Aditya, Sebastián Sosa-Carrillo, Sébastien Gilles, François Bertaux, Jakob Ruess, Gregory Batt   +8 more
openaire   +1 more source

The Fate (Outcome) of Clinically Apparent Single Lesion and Oligofocal Nephroblastomatosis Treated According to SIOP/GPOH Protocols for Wilms Tumor

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The management of clinically apparent single lesions or oligofocal nephroblastomatosis, a facultative precursor of nephroblastoma, remains debated. Methods We retrospectively analyzed 37 patients with clinically apparent single or oligofocal nephroblastomatosis (two to three lesions per kidney) among 2347 patients registered between
Nils Welter, Jens‐Peter Schenk, Jenny Wegert, Manfred Gessler, Leo Kager, Stefan Wagenpfeil, Marina Müller, Jean‐Michel Wolff, Joerg Fuchs, Steven W. Warmann, Clemens‐Magnus Meier, Jochen Hubertus, Christian Rübe, Christian Vokuhl, Patrick Melchior, Lena Tschirner, Norbert Graf, Rhoikos Furtwängler   +17 more
wiley   +1 more source

Lysosomal degradation of newly formed insulin granules contributes to β cell failure in diabetes

Nature Communications, 2019
Impaired beta-cell insulin secretion is a key pathological feature of type 2 diabetes. Here, the authors describe metabolic stress induced lysosomal degradation of newly formed insulin granules, independent of macroautophagy, as a potential mechanism for
Adrien Pasquier, Kevin Vivot, Eric Erbs, Coralie Spiegelhalter, Zhirong Zhang, Victor Aubert, Zengzhen Liu, Meryem Senkara, Elisa Maillard, Michel Pinget, Julie Kerr-Conte, François Pattou, Gilbert Marciniak, Axel Ganzhorn, Paolo Ronchi, Nicole L. Schieber, Yannick Schwab, Paul Saftig, Alexander Goginashvili, Romeo Ricci   +19 more
doaj   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

STM conductance of Kondo impurities on open and structured surfaces

, 2002
We study the scanning tunneling microscopy response for magnetic atoms on open and structured surfaces using Wilson's renormalization group. We observe Fano resonances associated with Kondo resonances and interference effects.
C. A. Balseiro, H.C. Manoharan, H.R. Krishna-murthy, J. Kondo, J. Li, K. Nagaoka, K.G. Wilson, M. Plihal, N. Knorr, O. Jeandupeux, O. Újsághy, P. S. Cornaglia, P. Simon, P.S. Cornaglia, P.S. Cornaglia, S. Pons, T.A. Costi, U. Fano, V. Madhavan, V. Madhavan   +19 more
core   +1 more source

Studies on the orientation of ACEL ZnS:Cu particles in applied AC fields [PDF]

, 2013
This article has been made available through the Brunel Open Access Publishing Fund.In the last sixty years the understanding of the mechanisms of alternating current electroluminescence (ACEL) in transition metaldoped zinc sulfides, in particular ZnS:Cu
Destriau, Fleet, Frondel, Ono, Oranovskij   +4 more
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source