Retraction: The botanical drug PBI-05204, a supercritical CO<sup>2</sup> extract of Nerium oleander, is synergistic with radiotherapy in models of human glioblastoma. [PDF]
Frontiers Editorial Office.
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Protocol for quantifying miRNA trafficking across the endosomal membrane
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Expression of Concern: Swaidan et al. Enhanced Antibacterial Activity of CuS-BSA/Lysozyme Under Near Infrared Light Irradiation. <i>Nanomaterials</i> 2021, <i>11</i>, 2156. [PDF]
Editorial Office N.
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Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia +9 more
wiley +1 more source
Correction: Effect and mechanism of Emodin on mouse myeloid-derived suppressor cells. [PDF]
Frontiers Production Office.
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GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Retraction: A new method for ethical and efficient evidence generation for off-label medication use in oncology (a case study in glioblastoma). [PDF]
Frontiers Editorial Office.
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Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
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