Results 221 to 230 of about 2,192,791 (336)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Referee report. For: A multi centre randomized open label trial of chloroquine for the treatment of adults with SARS-CoV-2 infection in Vietnam [version 1; peer review: 1 approved, 2 approved with reservations]

, 2020
Vanessa Bergamin Boralli
openalex   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Pennsylvania Libraries: Research & Practice - A new, peer-reviewed, online, Open Access journal [PDF]

, 2012
John H. Barnett
openalex  

Living in a Digital World: Rethinking Peer Review, Collaboration, and Open Access

, 2012
Sheila T. Cavanagh
openalex   +2 more sources

Peer Review #4 of "Blockchain for genomics and healthcare: a literature review, current status, classification and open issues (v0.1)"

, 2021

openalex   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Referee report. For: The European Open Science Cloud as a common good Potentials and limitations of this endeavour [version 1; peer review: 3 approved]

Rodrigo V. Honorato
openalex   +1 more source

Referee report. For: Metformin as adjunctive therapy for dengue in overweight and obese patients: a protocol for an open-label clinical trial (MeDO) [version 1; peer review: 2 approved]

, 2020
Quirijn de Mast
openalex   +1 more source

A retrospective analysis of submissions, acceptance rate, open peer review operations, and prepublication bias of the multidisciplinary open access journal Head & Face Medicine [PDF]

, 2007
Thomas Stamm, Ulrich Meyer, Hans‐Peter Wiesmann, Johannes Kleinheinz, Murat Cavit Çehreli, Zafer C. Çehreli   +5 more
openalex   +1 more source