Results 131 to 140 of about 3,790,328 (218)

Radiographic and clinical factors associated with open reduction in pediatric supracondylar humerus fractures. [PDF]

Ulus Travma Acil Cerrahi Derg
Kocazeybek E, Ersin M, Dogan Y, Savran F, Tatli A, Ekinci M.   +5 more
europepmc   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Determinants of Dehiscence and Wound Infections After Open Reduction and Internal Fixation of Femoral Shaft and Subtrochanteric fractures. [PDF]

Orthop Rev (Pavia)
Abdelrahman M, Stead TS, Chillakuru R, Ganti L.   +3 more
europepmc   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Open Reduction and Internal Fixation of a Comminuted Displaced Radial Head Fracture in a 12-Year-Old Female: A Case Report. [PDF]

J Orthop Case Rep
Veetil HHM, Jain A, Gulihar A, Gokaraju K.   +3 more
europepmc   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Short-term complications following distal humerus open reduction and internal fixation. [PDF]

JSES Int
Sribhashyam S, Talaski GM, Yazdanpanah S, Edge C, Smith MS, Cuthbert AS, Vanderbeck JL.   +6 more
europepmc   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

Acromion type III scapular spine nonunion open reduction internal fixation with distal clavicular and pelvic plates. [PDF]

JSES Rev Rep Tech
Gorsky AL, Seilern Und Aspang J, Blevins KM, Chopra KN, Gottschalk MB, Wagner ER.   +5 more
europepmc   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source