Results 121 to 130 of about 8,610,280 (359)

The Ninth National Information Day: Open Science, Open Data, Open Access

Digital Presentation and Preservation of Cultural and Scientific Heritage, 2018
The paper draws current state of Bulgarian Open access (OA) activities and discussion points for the Ninth National Information Day: Open Science, Open Data, and Open Access.
Peter Stanchev, Milena Damyanova, Yanita Zherkova, Zlatina Karova, Guenoveva Jecheva, Radoslav Pavlov, George Simeonov   +6 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Open (citizen) science: Prospects and open issues [PDF]

Družboslovne Razprave
The article discusses the significance of open science, notably the concept of citizen science, within a broader sociopolitical and socio-scientific context.
Frane Adam, Maruša Gorišek
doaj  

Using open science principles for open science advocacy

, 2019
The eeFDM project that aims at developing components for an effective and efficient research data management (RDM) was funded by the BMBF in 2017. As for most RDM projects, a significant amount of energy is put into outreach and teaching initiatives.
Colomb, Julien, Gerlach, Roman
openaire   +3 more sources

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

FEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield, Torsten Kleffmann, David J. Saul, Sigurd M. Wilbanks   +3 more
wiley   +1 more source

Extending Awareness of Open Science via Peers: The ERUA Open Science Ambassador Programme

Liber Quarterly: The Journal of European Research Libraries
Reaching researchers in terms of Open Science-related matters is a big challenge for Open Science professionals. To encourage peer exchange among researchers working at universities of the European Reform University Alliance (ERUA), we launched the ERUA
Sonja N. Kralj, Maximilian Heber, Paulina Helmecke   +2 more
doaj   +1 more source

Das Open Science Network Austria (OANA) und seine Arbeitsgruppe “Rechtliche Aspekte von Open Science”

Mitteilungen der Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare, 2019
In diesem Beitrag wird das Open Science Network Austria (OANA) vorgestellt. Die Entwicklung und Struktur des Netzwerks werden einleitend beschrieben, bevor Open Science einerseits als allgemeiner Begriff, andererseits in der Definition von OANA umrissen ...
Vanessa Hannesschläger
doaj   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

Bulgarian Open Science Digital Library - First Prototype

Digital Presentation and Preservation of Cultural and Scientific Heritage, 2019
In this paper we present the process of development of Bulgarian Open Science Digital Library (BOSDL) as the first and main ingredient of Bulgarian Open Science Cloud (BOSC). We introduce and discuss main principles involved in the Open Science movement.
Atanas Georgiev, Krassen Stefanov
doaj   +1 more source