Results 151 to 160 of about 8,610,280 (359)

Berlin's second Academy of Sciences opens [PDF]

, 1987
Steven Dickman
openalex   +1 more source

An open science study of ageing in companion dogs

Nature, 2022
K. Creevy, J. Akey, M. Kaeberlein, D. Promislow, Brian G. Brooke Elhanan Marta G. Lucy Devin Amanda E. Ky Barnett Benton Borenstein Castelhano Chou Collins , Brian G. Barnett, B. Benton, Elhanan Borenstein, M. Castelhano, Lucy Chou, D. Collins, A. Coleman, Kyle Crowder, M. Dunbar, Jeremy Evans, V. Fajt, Annette L. Fitzpatrick, U. Jeffery, Erica C. Jonlin, E. Karlsson, Kathleen F. Kerr, Hannah Lee, J. Levine, Jing Ma, R. McClelland, Kelly McNulty, Kathleen Morrill, Yunbi Nam, A. Ruple, Stephen M. Schwartz, Sandi Shrager, N. Snyder‐Mackler, W. Thistlethwaite, A. Tinkle, M. Tolbert, S. Urfer, B. Wilfond   +36 more
semanticscholar   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

FEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer, Philip Hinchliffe, Marko Hanževački, Christopher R. Bethel, Catherine L. Tooke, Marc W. Van der Kamp, Krisztina M. Papp‐Wallace, Robert A. Bonomo, Stuart Shapiro, Adrian J. Mulholland, James Spencer   +10 more
wiley   +1 more source

Genetically Engineered Organisms Benefits and Risks. By J. R. S. Fincham and J. R. Ravetz, in collaboration with a working party of the Council for Science and Society. Open University Press, Buckingham MK18 1XW, UK. 1991. 158 pages. Hardback £27.50, ISBN 0 335 096190; paperback £8.99, ISBN 0 335 09618 2. [PDF]

, 1991
Eric Reeve
openalex   +1 more source

Contextualizing Openness: Situating Open Science.

, 2019
Zenodo (2019).
Chan, Leslie, Okune, Angela, Hillyer, Rebecca, Albornoz, Dennise, Posada, Alejandro   +4 more
openaire   +3 more sources

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

Science GLAM and Open Science

, 2021
This repository contains a presentation given remotely on October 13, 2021 in Jakarta as part of the 4th International Conference on Documentation and Information. The acronym "GLAM" stands for "Galleries, Libraries, Archives and Museums" and is used as a shorthand for the heritage sector more generally.
openaire   +2 more sources

Novel and unscrutinized immune entities of the zebrafish gut

FEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil, Marine Mantel, Julia Soh, Serge Mostowy, Sylvia Brugman, Gilles Claude Vanwalleghem   +5 more
wiley   +1 more source

Solving medicine’s data bottleneck: Nightingale Open Science

Nature Network Boston, 2022
S. Mullainathan, Z. Obermeyer
semanticscholar   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source