Results 161 to 170 of about 8,610,280 (359)

The Moral Schizophrenia in the Fight Against Big Publisha

open access: yesDutch Journal of Applied Linguistics
In this contribution, Ali Al-Hoorie considers open science from a global South perspective and proposes a three-stage roadmap towards scholarship that is truly equitable.
Ali Al-Hoorie
doaj   +1 more source

Open for Science

open access: yes, 2021
"Open for Science" is a presentation by Dr Kevin Moerman and is aimed at informing academics about the benefits of open science and how to be an open scientist. This talk was presented as part of a symposium for the SFI research centre LERO, as well as for the PERFORM training network.
openaire   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

open access: yesFEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri   +5 more
wiley   +1 more source

Addressing bias in big data and AI for health care: A call for open science

open access: yesPatterns, 2021
Natalia Norori   +4 more
semanticscholar   +1 more source

Protein kinase FAM20C—when subcellular localization matters

open access: yesFEBS Letters, EarlyView.
FAM20C is a Golgi‐resident kinase that phosphorylates proteins along the entire secretory pathway. The presence of potential FAM20C substrates in the cytoplasm or nucleus raises the question of how the kinase and its substrates encounter each other. Protein kinases achieve signaling specificity through consensus sequence recognition and subcellular ...
Francesca Noventa, Mauro Salvi
wiley   +1 more source

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