Results 241 to 250 of about 8,389,625 (348)

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

NASA open science data repository: open science for life in space. [PDF]

Nucleic Acids Res
Gebre SG, Scott RT, Saravia-Butler AM, Lopez DK, Sanders LM, Costes SV.   +5 more
europepmc   +1 more source

Empfehlungen für eine nationale Open Science Strategie in Österreich / Recommendations for a National Open Science Strategy in Austria

, 2020
Katja Mayer, Katharina Rieck, Stefan Reichmann, Patrick Danowski, Anton Graschopf, Thomas König, Peter Kraker, Patrick Lehner, Falk Reckling, Tony Ross‐Hellauer, Daniel Spichtinger, Michalis Tzatzanis, Stefanie Schürz   +12 more
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Open Science και μετάφραση

Cybergeo, 2020
Christine Kosmopoulos
doaj  

Open Science practices in a Portuguese nursing higher education institution: An exploratory, descriptive study. [PDF]

PLoS One
Sousa AS, Lopes M, Rodrigues D, Oliveira P, Pires R, Pinto S, Melo P, Rosa JF, Alves A, Silva R.   +9 more
europepmc   +1 more source

How I Learned to Stop Worrying and Love Open Science - Tomas Knapen, Keynote Talk #SciData19

, 2019
Scientific Data, Tomas Knapen
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Open science and translation

Cybergeo, 2020
Christine Kosmopoulos
doaj  

Could Open Science stimulate industry partnerships in Chemical Engineering university research?

, 2020
Kirsten Hart, Sung Jun An, A.M. Edwards, Radhakrishnan Mahadevan, Emma R. Master, Elizabeth A. Edwards   +5 more
openalex   +1 more source