Results 321 to 330 of about 8,610,280 (359)

A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer

Molecular Oncology, EarlyView.
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla, Jana R. Crespo, Saioa Garcia‐Longarte, Marta Fidalgo, Sara del Palacio, Natalia Martin‐Martin, Onintza Carlevaris, Ianire Astobiza, Sonia Fernández‐Ruiz, Marc Guiu, Laura Bárcena, Isabel Mendizabal, Ana M. Aransay, Mariona Graupera, Roger R. Gomis, Arkaitz Carracedo   +15 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Editorial: Open science to support replicability in neuroergonomic research. [PDF]

Front Neuroergon
Gramann K, Lotte F, Dehais F, Ayaz H, Vukelić M, Karwowski W, Fairclough S, Brouwer AM, Roy RN.   +8 more
europepmc   +1 more source

State of open science in cancer research. [PDF]

Clin Transl Oncol
Rius C, Liu Y, Sixto-Costoya A, Valderrama-Zurián JC, Lucas-Dominguez R.   +4 more
europepmc   +1 more source

Let's celebrate Earth Day as the Age of Open Science. [PDF]

Sci Adv
Naeem S, Jackson J, Neelin D.
europepmc   +1 more source

Open science and phenotyping in UK administrative health, education and social care data: the ECHILD phenotype code list repository. [PDF]

Int J Popul Data Sci
Jay MA, Lewis K, Shi D, Langella R, Stone T, Chobhthaigh SN, Zylbersztejn A, Blackburn R, Harron K.   +8 more
europepmc   +1 more source

"Best Paper" awards lack transparency, inclusivity, and support for Open Science. [PDF]

PLoS Biol
Lagisz M, Rutkowska J, Aich U, Ross RM, Santana MS, Wang J, Trubanová N, Page MJ, Pua AAY, Yang Y, Amin B, Martinig AR, Barnett A, Surendran A, Zhang J, Borg DN, Elisee J, Wrightson JG, Nakagawa S.   +18 more
europepmc   +1 more source

CyVerse: Cyberinfrastructure for open science. [PDF]

PLoS Comput Biol
Swetnam TL, Antin PB, Bartelme R, Bucksch A, Camhy D, Chism G, Chism G, Choi I, Cooksey AM, Cosi M, Cowen C, Culshaw-Maurer M, Davey R, Davey S, Devisetty U, Edgin T, Edmonds A, Fedorov D, Frady J, Fonner J, Gillan JK, Hossain I, Joyce B, Lang K, Lee T, Littin S, McEwen I, Merchant N, Micklos D, Nelson A, Ramsey A, Roberts S, Sarando P, Skidmore E, Song J, Sprinkle MM, Srinivasan S, Stanzione D, Strootman JD, Stryeck S, Tuteja R, Vaughn M, Wali M, Wall M, Walls R, Wang L, Wickizer T, Williams J, Wregglesworth J, Lyons E.   +49 more
europepmc   +1 more source