Results 71 to 80 of about 8,389,625 (348)

Open Notebook Science Challenge: Solubilities of Organic Compounds in Organic Solvents [PDF]

open access: yes, 2010
This book contains the results of the Open Notebook Science Solubility Challenge. All experimental measurements are provided with a link to either the laboratory notebook page where the experiment was carried out or to a literature reference.
Andrew Lang   +17 more
core   +6 more sources

Achievements, Experience and Improvement Countermeasures of International Organizations in Promoting the Development of Open Science——Taking IKCEST as an Example

open access: yesZhishi guanli luntan, 2022
[Purpose/Significance] Open Science, as a revolutionary system engineering, is faced up with many challenges in its evolution, for which it needs to break through the limitations of multiple barriers between nations, expertise, narrow
Fang Ying
doaj   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Fostering open science practice through recognising and rewarding research data management and curation skills [PDF]

open access: yes, 2016
In a bid to improve research integrity, drive innovation, increase knowledge and to maximize public investment, researchers are increasingly under pressure to work in a more open and transparent way.
Davidson, Joy
core   +1 more source

Library for Open Science

open access: yesБиблиосфера, 2023
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article Editorial
doaj  

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

An Atheistic Defence of Christian Science [PDF]

open access: yes, 2013
Should the Christian community engage in Christian science  – doing science starting from the standpoint of the Christian evidence base? Plantinga asks this question, and I  argue that the answer is ‘yes’.
Bradley, Monton
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Open access journals: transparent science or shady business? [PDF]

open access: yes, 2019
OA journals consequences for Science/ The scientific community; OA journals advantages/disadvantages for the publisher/reader/author; What can be done?N/
Botelho, M., Richter, J.
core  

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