Results 231 to 240 of about 1,040,059 (296)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Food environments provide availability and physical access to vegetables in urban Benin and Mali. [PDF]

Public Health Nutr
Clarke RN, Traore O, Orphyse AR, Sidibe A, Cisse F, Fanou-Fogny N, Dou Y, Harris J.   +7 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Optimizing energy, downtime, and throughput in footwear production through machine learning. [PDF]

Sci Rep
Sudhakar PK, Muthucumaraswamy R.
europepmc   +1 more source

Perspectives From Canadian People With Visual Impairments in Everyday Environments Outside the Home: Qualitative Insights for Assistive Technology Development. [PDF]

JMIR Rehabil Assist Technol
Puri PR, Coutaller A, Gwade F, Kabore SS, Annan D, Nemargut JP.   +5 more
europepmc   +1 more source

Internet Searches for Lorazepam Following the Release of The White Lotus.

JAMA Health Forum
Yang KH, Satybaldiyeva N, Kepner W, Friedman J, Leas EC.   +4 more
europepmc   +1 more source

General and Toxicologic Aspects of Occupational Fatalities in the Metropolitan Area of Lyon From 2000 to 2020, a Retrospective Study. [PDF]

Med Lav
Lamouroux C, Pouliquen G, Fort E, Epain M, Marfaing F, Charbotel B, Fanton L.   +6 more
europepmc   +1 more source

A system for invitro inhaled/exhaled aerosol testing of personal protective equipment. [PDF]

Sci Rep
Baldelli A, Poznikoff A, Purdy R.
europepmc   +1 more source

Exploring documentation and reporting practices in malaria tracking: a mixed-methods study among formal drug retail shops in Hohoe Municipal, Ghana. [PDF]

Malar J
Loglo V, Gmayinaam VU, Ampomah MA, Boateng P, Ansah EK.   +4 more
europepmc   +1 more source