Results 81 to 90 of about 1,040,059 (296)

Door Hanger - Open Access Week at Gettysburg College

, 2014
This print marketing piece was designed to complement online promotion of Open Access Week 2014 at Gettysburg College. Door hangers provide a brief description of OA Week events aimed at faculty.
Musselman Library,
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Community Benefits and Lessons for Local Engagement in a California Open Streets Event: A Mixed-Methods Assessment of Viva CalleSJ 2018 [PDF]

, 2019
This report presents the findings from an evaluation of the September 2018 Viva CalleSJ open streets event in San José,CA. The research was designed to assess the success of the event, guide planning for future open streets events, and inform potential ...
Agrawal, Asha Weinstein, Currin-Percival, Mary, Cushing, Katherine, DeHaan, Jason, Douglas, Gordon   +4 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Enhancing Industrial Digitalisation through an Adaptable Component for Bridging Semantic Interoperability Gaps

Applied Sciences
Digital transformation has a great effect on industries but also in the perception of their products with high consequences on society as a whole, as driver for innovation.
Diego F. Carvajal-Flores, Patricia Abril-Jiménez, Eduardo Buhid, Giuseppe Fico, María Fernanda Cabrera Umpiérrez   +4 more
doaj   +1 more source

La « Cave aux Amphores » d’Alesia (Alise-Sainte-Reine, Côte-d’Or) : nouvelle lecture à l'issue d'une opération archéologique récente

Revue Archéologique de l’Est, 2008
Following extensive damage of the masonry of a Gallo-Roman cellar discovered in 1934 on the site of Alésia (Alise-Sainte-Reine), and left open ever since, an archaeological survey was carried out before its restoration in 2004. This building presents the
Jérôme Mercier
doaj   +1 more source

Who Will Build the Future? [PDF]

, 1988
[Excerpt] The construction unions\u27 crisis both preceded and contributed to the general decline of organized labor. At the time concessions became a household word in manufacturing, building trades workers had already endured five years of wage ...
Erlich, Mark
core   +1 more source