Results 61 to 70 of about 699,612 (287)
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
EpiFire: An open source C++ library and application for contact network epidemiology
BMC Bioinformatics, 2012 Background Contact network models have become increasingly common in epidemiology, but we lack a flexible programming framework for the generation and analysis of epidemiological contact networks and for the simulation of disease transmission through ...
Hladish Thomas +4 more
doaj +1 more source
A Rotational Pressure-Correction Scheme for Incompressible Two-Phase Flows with Open Boundaries. [PDF]
PLoS ONE, 2016 Two-phase outflows refer to situations where the interface formed between two immiscible incompressible fluids passes through open portions of the domain boundary. We present several new forms of open boundary conditions for two-phase outflow simulations
S Dong, X Wang
doaj +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
The Theoretical Astrophysical Observatory: Cloud-Based Mock Galaxy Catalogues
, 2016 We introduce the Theoretical Astrophysical Observatory (TAO), an online virtual laboratory that houses mock observations of galaxy survey data. Such mocks have become an integral part of the modern analysis pipeline.
Bernyk, Maksym +9 more
core +3 more sources
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Shiyou jixie, 2020 The migration and leakage of formation fluid to the ground along the cement plug/formation interface imposed adversely influences on wellbore seal integrity of open hole temporary abandoned wells.
Jiang Jiwei +4 more
doaj
He jishu, 2023 BackgroundNuclear power simulation technology has been widely applied in areas such as reactor design, safety analysis, independent safety evaluation, accident mitigation measures, design and optimization of control and protection system, verification of
CHEN Shichao +6 more
doaj +1 more source
Python bindings for the open source electromagnetic simulator Meep [PDF]
, 2011 Meep is a broadly used open source package for finite-difference time-domain electromagnetic simulations. Python bindings for Meep make it easier to use for researchers and open promising opportunities for integration with other packages in the Python ...
Bienstman, Peter +6 more
core +1 more source