Results 151 to 160 of about 2,742,145 (306)

The path to adoption of open source AI for drug discovery in Africa

Artificial Intelligence in the Life Sciences
Gemma Turon, Miquel Duran-Frigola
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Flüssiger Code - Open Source Software in der Medienkunst

, 2007
Im Rahmen dieses Artikels wird ein Überblick über die Anwendung von Open Source Software im Bereich der Kunst - hier vor allem den verschiedenen Spielarten der Medienkunst - gegeben.
Pichlmair, Martin
core  

Editorial: Alleviating age-related disease burden

Frontiers in Aging
Matthew Halma, Sidra Hassaan, Jack A. Tuszynski, Jack A. Tuszynski   +3 more
doaj   +1 more source

FilmQADose: Open-source software for radiochromic film dosimetry. [PDF]

J Appl Clin Med Phys
Herrera-Alba E, Contreras-Quiroz C, Sandoval-Navia J, Vásquez J, Ávila C.   +4 more
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Machine Learning Approaches Identify Chemical Features for Stage-Specific Antimalarial Compounds

ACS Omega, 2023
Ashleigh van Heerden, Gemma Turon, Miquel Duran-Frigola, Nelishia Pillay, Lyn-Marié Birkholtz   +4 more
doaj   +1 more source

Open-Source Multinuclear Low-Field Preclinical MRI Scanner. [PDF]

NMR Biomed
Rodriguez GG, Korchak S, von Petersdorff-Campen C, Sucre O, Felger J, Mei R, Glöggler S.   +6 more
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

PAPRECA: a parallel hybrid off-lattice kinetic Monte Carlo/molecular dynamics simulator

Kinetic Monte Carlo (kMC) is an atomistic and stochastic simulation technique that captures the temporal evolution of various systems in materials science, chemistry, physics, biology, and engineering.
Ntioudis, Stavros, Dini, Daniele, Turner, C Heath, Ewen, James P   +3 more
core   +1 more source