Results 181 to 190 of about 16,728,413 (378)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

IDPEnsembleTools: An open-source library for analysis of conformational ensembles of disordered proteins. [PDF]

Protein Sci
Ghafouri H, Janson G, Tosatto SCE, Monzon AM.   +3 more
europepmc   +1 more source

PENGEMBANGAN BUSSINESS INTELEGENCE (BI) UNTUK PERUSAHAAN DALAM MEMBANGUN SOLUSI BISNIS BERBASIS OPEN SOURCE

, 2015
Ferry Sudarto, Diah Aryani, Yulianto Yulianto   +2 more
openalex   +2 more sources

Open source health systems [PDF]

, 2005
Forslund, D, Kalra, D
core  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

heXRD: Modular, Open Source Software for the Analysis of High Energy X-Ray Diffraction Data

, 2013
Donald E. Boyce, Joel V. Bernier
openalex   +2 more sources

Open Source & Open Data

, 2019
Proyectos de Código Abierto (Open Source) y de Acceso Abierto (Open Access) han definido y siguen dando forma a grandes desarrollos en la ciencia fundamental y las tecnologías de la información.Desde hace mucho tiempo, pero más aun hoy en día, empresas científicas y colaboraciones académicas impulsan un basto set de proyectos Open Source en términos de
openaire   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

An open-source underwater robotics platform for aquatic research & exploration. [PDF]

HardwareX
Mayberry S, Cai J, Yang R, Wang J, Zhang F.   +4 more
europepmc   +1 more source

An investigation of software vulnerabilities in open source software projects using data from publicly-available online sources.

, 2017
Syed Mansoob Murshed
openalex   +2 more sources